Structural remodeling of ribosome associated Hsp40-Hsp70 chaperones during co-translational folding
Ribosome associated complex (RAC)- HSP70 (Ssb in yeast) is a eukaryotic chaperone system involved in co-translational folding. Here, authors report structures of RAC-containing ribosomal complexes, which suggest a working model for the dynamic actions of RAC-Ssb during the process.
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-06-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-31127-4 |
| _version_ | 1811342878396383232 |
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| author | Yan Chen Bin Tsai Ningning Li Ning Gao |
| author_facet | Yan Chen Bin Tsai Ningning Li Ning Gao |
| author_sort | Yan Chen |
| collection | DOAJ |
| description | Ribosome associated complex (RAC)- HSP70 (Ssb in yeast) is a eukaryotic chaperone system involved in co-translational folding. Here, authors report structures of RAC-containing ribosomal complexes, which suggest a working model for the dynamic actions of RAC-Ssb during the process. |
| first_indexed | 2024-04-13T19:19:46Z |
| format | Article |
| id | doaj.art-1db20a78d47844ba8f52a00cc826e16d |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-13T19:19:46Z |
| publishDate | 2022-06-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-1db20a78d47844ba8f52a00cc826e16d2022-12-22T02:33:34ZengNature PortfolioNature Communications2041-17232022-06-0113111410.1038/s41467-022-31127-4Structural remodeling of ribosome associated Hsp40-Hsp70 chaperones during co-translational foldingYan Chen0Bin Tsai1Ningning Li2Ning Gao3State Key Laboratory of Membrane Biology, School of Life Science, Tsinghua UniversityState Key Laboratory of Membrane Biology, Peking-Tsinghua Joint Center for Life Sciences, School of Life Sciences, Peking UniversityState Key Laboratory of Membrane Biology, Peking-Tsinghua Joint Center for Life Sciences, School of Life Sciences, Peking UniversityState Key Laboratory of Membrane Biology, Peking-Tsinghua Joint Center for Life Sciences, School of Life Sciences, Peking UniversityRibosome associated complex (RAC)- HSP70 (Ssb in yeast) is a eukaryotic chaperone system involved in co-translational folding. Here, authors report structures of RAC-containing ribosomal complexes, which suggest a working model for the dynamic actions of RAC-Ssb during the process.https://doi.org/10.1038/s41467-022-31127-4 |
| spellingShingle | Yan Chen Bin Tsai Ningning Li Ning Gao Structural remodeling of ribosome associated Hsp40-Hsp70 chaperones during co-translational folding Nature Communications |
| title | Structural remodeling of ribosome associated Hsp40-Hsp70 chaperones during co-translational folding |
| title_full | Structural remodeling of ribosome associated Hsp40-Hsp70 chaperones during co-translational folding |
| title_fullStr | Structural remodeling of ribosome associated Hsp40-Hsp70 chaperones during co-translational folding |
| title_full_unstemmed | Structural remodeling of ribosome associated Hsp40-Hsp70 chaperones during co-translational folding |
| title_short | Structural remodeling of ribosome associated Hsp40-Hsp70 chaperones during co-translational folding |
| title_sort | structural remodeling of ribosome associated hsp40 hsp70 chaperones during co translational folding |
| url | https://doi.org/10.1038/s41467-022-31127-4 |
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