Composition-based statistics and translated nucleotide searches: Improving the TBLASTN module of BLAST

Composition-based statistics and translated nucleotide searches: Improving the TBLASTN module of BLAST

<p>Abstract</p> <p>Background</p> <p>TBLASTN is a mode of operation for BLAST that aligns protein sequences to a nucleotide database translated in all six frames. We present the first description of the modern implementation of TBLASTN, focusing on new techniques that w...

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Bibliographic Details
Main Authors:	Schäffer Alejandro A, Agarwala Richa, Yu Yi-Kuo, Gertz E Michael, Altschul Stephen F
Format:	Article
Language:	English
Published:	BMC 2006-12-01
Series:	BMC Biology
Online Access:	http://www.biomedcentral.com/1741-7007/4/41

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