Gene network inference from single-cell omics data and domain knowledge for constructing COVID-19-specific ICAM1-associated pathways

Gene network inference from single-cell omics data and domain knowledge for constructing COVID-19-specific ICAM1-associated pathways

Introduction: Intercellular adhesion molecule 1 (ICAM-1) is a critical molecule responsible for interactions between cells. Previous studies have suggested that ICAM-1 triggers cell-to-cell transmission of HIV-1 or HTLV-1, that SARS-CoV-2 shares several features with these viruses via interactions b...

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Bibliographic Details
Main Authors: Mitsuhiro Odaka, Morgan Magnin, Katsumi Inoue
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Genetics
Subjects:
ICAM-1
cell-to-cell transmission
COVID-19
single-cell omics data analysis
model validation
pathway enrichment analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1250545/full

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