YY1 promotes pancreatic cancer cell proliferation by enhancing mitochondrial respiration

YY1 promotes pancreatic cancer cell proliferation by enhancing mitochondrial respiration

Abstract KRAS-driven metabolic reprogramming is a known peculiarity features of pancreatic ductal adenocarcinoma (PDAC) cells. However, the metabolic roles of other oncogenic genes, such as YY1, in PDAC development are still unclear. In this study, we observed significantly elevated expression of YY...

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Bibliographic Details
Main Authors: Bin Li, Junyi Wang, Jing Liao, Minghui Wu, Xiangshu Yuan, Hezhi Fang, Lijun Shen, Minghua Jiang
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Cancer Cell International
Subjects:
YY1
PDAC
OXPHOS
Nucleotide metabolism
Aspartate
Online Access:https://doi.org/10.1186/s12935-022-02712-w

Internet

https://doi.org/10.1186/s12935-022-02712-w

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