Platelet-rich plasma versus corticosteroid injections for rotator cuff tendinopathy: a comparative study with up to 18-month follow-up
Background Given the complications involved in corticosteroid (CS) injections, subacromial platelet-rich plasma (PRP) injections may provide a valid alternative to CS in the treatment of rotator cuff (RC) tendinopathy. Methods We retrospectively reviewed a total of 98 patients affected by RC tendino...
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| Format: | Article |
| Language: | English |
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Korean Shoulder and Elbow Society
2022-03-01
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| Series: | Clinics in Shoulder and Elbow |
| Subjects: | |
| Online Access: | http://www.cisejournal.org/upload/pdf/cise-2021-00486.pdf |
| _version_ | 1827361578351067136 |
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| author | Juho Aleksi Annaniemi Jüri Pere Salvatore Giordano |
| author_facet | Juho Aleksi Annaniemi Jüri Pere Salvatore Giordano |
| author_sort | Juho Aleksi Annaniemi |
| collection | DOAJ |
| description | Background Given the complications involved in corticosteroid (CS) injections, subacromial platelet-rich plasma (PRP) injections may provide a valid alternative to CS in the treatment of rotator cuff (RC) tendinopathy. Methods We retrospectively reviewed a total of 98 patients affected by RC tendinopathy who were treated with either subacromial injection of PRP or CS. The PRP group received three injections of autologous PRP at 2 weeks interval, and the CS group received one injection of CS. The Western Ontario Rotator Cuff Index (WORC) was the primary outcome measure, while the secondary outcome measures were the visual analog scale (VAS), range of motion (ROM), and need for cuff repair surgery, which were analyzed at intervals of 6, 12, and 18 months. Results A total of 75 patients were included in the analysis (PRP, n=35; CS, n=40). The mean follow-up for PRP was 21.1±8.7 months and for CS was 33.6±16.3 months (p<0.001). Both groups showed improvement in WORC, VAS, and ROM. No significant differences were detected between the two groups in any of the primary (WORC) or secondary outcomes over 6, 12, and 18 months (all p>0.05). No adverse events were detected. Conclusions Both treatments improved patient symptoms, but neither resulted in a significantly better outcome in this series of patients. PRP can be a safe and feasible alternative to CS, even at long-term follow-up, to reduce local and systemic effects involved with CS injections. |
| first_indexed | 2024-03-08T07:07:26Z |
| format | Article |
| id | doaj.art-1dbbd99eb9974121ab12da0c26ae0ffb |
| institution | Directory Open Access Journal |
| issn | 2288-8721 |
| language | English |
| last_indexed | 2024-03-08T07:07:26Z |
| publishDate | 2022-03-01 |
| publisher | Korean Shoulder and Elbow Society |
| record_format | Article |
| series | Clinics in Shoulder and Elbow |
| spelling | doaj.art-1dbbd99eb9974121ab12da0c26ae0ffb2024-02-03T04:08:52ZengKorean Shoulder and Elbow SocietyClinics in Shoulder and Elbow2288-87212022-03-01251283510.5397/cise.2021.00486840Platelet-rich plasma versus corticosteroid injections for rotator cuff tendinopathy: a comparative study with up to 18-month follow-upJuho Aleksi Annaniemi0Jüri Pere1Salvatore Giordano2 Department of Surgery, Welfare District of Forssa, University of Turku, Forssa, Finland Department of Surgery, Welfare District of Forssa, University of Turku, Forssa, Finland Department of General and Plastic Surgery, Turku University Hospital, University of Turku, Turku, FinlandBackground Given the complications involved in corticosteroid (CS) injections, subacromial platelet-rich plasma (PRP) injections may provide a valid alternative to CS in the treatment of rotator cuff (RC) tendinopathy. Methods We retrospectively reviewed a total of 98 patients affected by RC tendinopathy who were treated with either subacromial injection of PRP or CS. The PRP group received three injections of autologous PRP at 2 weeks interval, and the CS group received one injection of CS. The Western Ontario Rotator Cuff Index (WORC) was the primary outcome measure, while the secondary outcome measures were the visual analog scale (VAS), range of motion (ROM), and need for cuff repair surgery, which were analyzed at intervals of 6, 12, and 18 months. Results A total of 75 patients were included in the analysis (PRP, n=35; CS, n=40). The mean follow-up for PRP was 21.1±8.7 months and for CS was 33.6±16.3 months (p<0.001). Both groups showed improvement in WORC, VAS, and ROM. No significant differences were detected between the two groups in any of the primary (WORC) or secondary outcomes over 6, 12, and 18 months (all p>0.05). No adverse events were detected. Conclusions Both treatments improved patient symptoms, but neither resulted in a significantly better outcome in this series of patients. PRP can be a safe and feasible alternative to CS, even at long-term follow-up, to reduce local and systemic effects involved with CS injections.http://www.cisejournal.org/upload/pdf/cise-2021-00486.pdfplatelet-rich plasmaadrenal cortex hormonesinjectionsrotator cufftendinopathyshoulder pain |
| spellingShingle | Juho Aleksi Annaniemi Jüri Pere Salvatore Giordano Platelet-rich plasma versus corticosteroid injections for rotator cuff tendinopathy: a comparative study with up to 18-month follow-up Clinics in Shoulder and Elbow platelet-rich plasma adrenal cortex hormones injections rotator cuff tendinopathy shoulder pain |
| title | Platelet-rich plasma versus corticosteroid injections for rotator cuff tendinopathy: a comparative study with up to 18-month follow-up |
| title_full | Platelet-rich plasma versus corticosteroid injections for rotator cuff tendinopathy: a comparative study with up to 18-month follow-up |
| title_fullStr | Platelet-rich plasma versus corticosteroid injections for rotator cuff tendinopathy: a comparative study with up to 18-month follow-up |
| title_full_unstemmed | Platelet-rich plasma versus corticosteroid injections for rotator cuff tendinopathy: a comparative study with up to 18-month follow-up |
| title_short | Platelet-rich plasma versus corticosteroid injections for rotator cuff tendinopathy: a comparative study with up to 18-month follow-up |
| title_sort | platelet rich plasma versus corticosteroid injections for rotator cuff tendinopathy a comparative study with up to 18 month follow up |
| topic | platelet-rich plasma adrenal cortex hormones injections rotator cuff tendinopathy shoulder pain |
| url | http://www.cisejournal.org/upload/pdf/cise-2021-00486.pdf |
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