Hand grip strength in patients with chronic obstructive pulmonary disease
Moa Jeong,1 Hyung Koo Kang,1 Pamela Song,2 Hye Kyeong Park,1 Hoon Jung,1 Sung-Soon Lee,1 Hyeon-Kyoung Koo1 1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, 2Department of Neurology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Republic of Kore...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2017-08-01
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| Series: | International Journal of COPD |
| Subjects: | |
| Online Access: | https://www.dovepress.com/hand-grip-strength-in-patients-with-chronic-obstructive-pulmonary-dise-peer-reviewed-article-COPD |
| _version_ | 1819230402616754176 |
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| author | Jeong M Kang HK Song P Park HK Jung H Lee SS Koo HK |
| author_facet | Jeong M Kang HK Song P Park HK Jung H Lee SS Koo HK |
| author_sort | Jeong M |
| collection | DOAJ |
| description | Moa Jeong,1 Hyung Koo Kang,1 Pamela Song,2 Hye Kyeong Park,1 Hoon Jung,1 Sung-Soon Lee,1 Hyeon-Kyoung Koo1 1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, 2Department of Neurology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Republic of Korea Purpose: Hand grip strength (HGS) is a simple way of predicting the risk of cardiovascular disease and all-cause mortality in the general population. However, the practical significance of grip strength in patients with COPD is uncertain. The aim of this study was to compare HGS between subjects with and without COPD and to evaluate its clinical relevance in patients with COPD by using a national survey.Methods: Data were collected from the Korean National Health and Nutrition Examination Survey. The study included 421 adults with COPD and 2,542 controls who completed questionnaires, spirometry, and a HGS test. HGS was compared between subjects with and without COPD, and the association between grip strength, lung function, and quality of life (QoL) was evaluated.Results: The mean HGS was 33.3±9.1 kg in the COPD group and 29.9±9.5 kg in the non-COPD group; adjusted HGS was 30.9±0.33 kg and 30.9±0.11 kg, respectively (P=0.99). HGS was not related to forced vital capacity (β=0.04, P=0.70) or forced expiratory volume in 1 second (β=0.11, P=0.24) in multivariable analysis. HGS was independently associated with the EQ-5D index, but the relationship was stronger in the COPD group (β=0.30, P<0.001) than in the non-COPD group (β=0.21, P<0.001). The results were similar for each component of the EQ-5D, including mobility (β=-0.25, P<0.001), daily activity (β=-0.19, P=0.01), pain/discomfort (β=-0.32, P<0.001), and anxiety/depression (β=-0.16, P=0.01).Conclusion: HGS was not different between subjects with and without COPD, but was associated with QoL – including mobility, daily activity, pain/discomfort, and anxiety/depression – in patients with COPD. The HGS test could be used as a marker of QoL in patients with COPD and could assist risk stratification in clinical practice. Keywords: pulmonary disease, chronic obstructive, hand strength, respiratory function tests, quality of life, biomarker |
| first_indexed | 2024-12-23T11:28:30Z |
| format | Article |
| id | doaj.art-1dbfc1b9a68a48d89548f08d5f2524ef |
| institution | Directory Open Access Journal |
| issn | 1178-2005 |
| language | English |
| last_indexed | 2024-12-23T11:28:30Z |
| publishDate | 2017-08-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Journal of COPD |
| spelling | doaj.art-1dbfc1b9a68a48d89548f08d5f2524ef2022-12-21T17:48:52ZengDove Medical PressInternational Journal of COPD1178-20052017-08-01Volume 122385239034191Hand grip strength in patients with chronic obstructive pulmonary diseaseJeong MKang HKSong PPark HKJung HLee SSKoo HKMoa Jeong,1 Hyung Koo Kang,1 Pamela Song,2 Hye Kyeong Park,1 Hoon Jung,1 Sung-Soon Lee,1 Hyeon-Kyoung Koo1 1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, 2Department of Neurology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Republic of Korea Purpose: Hand grip strength (HGS) is a simple way of predicting the risk of cardiovascular disease and all-cause mortality in the general population. However, the practical significance of grip strength in patients with COPD is uncertain. The aim of this study was to compare HGS between subjects with and without COPD and to evaluate its clinical relevance in patients with COPD by using a national survey.Methods: Data were collected from the Korean National Health and Nutrition Examination Survey. The study included 421 adults with COPD and 2,542 controls who completed questionnaires, spirometry, and a HGS test. HGS was compared between subjects with and without COPD, and the association between grip strength, lung function, and quality of life (QoL) was evaluated.Results: The mean HGS was 33.3±9.1 kg in the COPD group and 29.9±9.5 kg in the non-COPD group; adjusted HGS was 30.9±0.33 kg and 30.9±0.11 kg, respectively (P=0.99). HGS was not related to forced vital capacity (β=0.04, P=0.70) or forced expiratory volume in 1 second (β=0.11, P=0.24) in multivariable analysis. HGS was independently associated with the EQ-5D index, but the relationship was stronger in the COPD group (β=0.30, P<0.001) than in the non-COPD group (β=0.21, P<0.001). The results were similar for each component of the EQ-5D, including mobility (β=-0.25, P<0.001), daily activity (β=-0.19, P=0.01), pain/discomfort (β=-0.32, P<0.001), and anxiety/depression (β=-0.16, P=0.01).Conclusion: HGS was not different between subjects with and without COPD, but was associated with QoL – including mobility, daily activity, pain/discomfort, and anxiety/depression – in patients with COPD. The HGS test could be used as a marker of QoL in patients with COPD and could assist risk stratification in clinical practice. Keywords: pulmonary disease, chronic obstructive, hand strength, respiratory function tests, quality of life, biomarker https://www.dovepress.com/hand-grip-strength-in-patients-with-chronic-obstructive-pulmonary-dise-peer-reviewed-article-COPDpulmonary diseasechronic obstructivehand strengthrespiratory function testsquality of lifebiomarker |
| spellingShingle | Jeong M Kang HK Song P Park HK Jung H Lee SS Koo HK Hand grip strength in patients with chronic obstructive pulmonary disease International Journal of COPD pulmonary disease chronic obstructive hand strength respiratory function tests quality of life biomarker |
| title | Hand grip strength in patients with chronic obstructive pulmonary disease |
| title_full | Hand grip strength in patients with chronic obstructive pulmonary disease |
| title_fullStr | Hand grip strength in patients with chronic obstructive pulmonary disease |
| title_full_unstemmed | Hand grip strength in patients with chronic obstructive pulmonary disease |
| title_short | Hand grip strength in patients with chronic obstructive pulmonary disease |
| title_sort | hand grip strength in patients with chronic obstructive pulmonary disease |
| topic | pulmonary disease chronic obstructive hand strength respiratory function tests quality of life biomarker |
| url | https://www.dovepress.com/hand-grip-strength-in-patients-with-chronic-obstructive-pulmonary-dise-peer-reviewed-article-COPD |
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