Targeting Nrf2 may reverse the drug resistance in ovarian cancer

Targeting Nrf2 may reverse the drug resistance in ovarian cancer

Abstract Background Acquired resistance to therapeutic drugs has become an important issue in treating ovarian cancer. Studies have shown that the prevalent chemotherapy resistance (cisplatin, paclitaxel etc.) for ovarian cancer occurs partly because of decreased production of reactive oxygen specie...

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Bibliographic Details
Main Authors: Danjie Li, Xiaoling Hong, Feijie Zhao, Xinxin Ci, Songling Zhang
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Cancer Cell International
Subjects:
Nrf2
Drug resistance
Reactive oxidative stress
Ovarian cancer
Online Access:https://doi.org/10.1186/s12935-021-01822-1

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