Synthesis and Pharmacological Evaluation of (+)-Usnic Acid Derivatives as Hypoglycemic Agents

Synthesis and Pharmacological Evaluation of (+)-Usnic Acid Derivatives as Hypoglycemic Agents

Usnic acid is produced by lichens and exhibits different biological properties, including hypoglycemic ones. However, this effect becomes noticeable only at relatively high doses, something that may lead to some adverse effects. The chemical modification of the molecule is able to enhance its safety...

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Bibliographic Details
Main Authors: Sergey A. Borisov, Olga A. Luzina, Mikhail V. Khvostov, Tatiana G. Tolstikova, Nariman F. Salakhutdinov
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Molbank
Subjects:
usnic acid
enamines
hypoglycemic action
diabetes mellitus
Online Access:https://www.mdpi.com/1422-8599/2022/4/M1459

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