Impact of glutamate levels on neuronal response and cognitive abilities in schizophrenia

Impact of glutamate levels on neuronal response and cognitive abilities in schizophrenia

Schizophrenia is characterized by impaired cognitive functioning, and brain regions involved in cognitive control processes show marked glutamatergic abnormalities. However, it is presently unclear whether aberrant neuronal response is directly related to the observed deficits at the metabolite leve...

Full description

Bibliographic Details
Main Authors:	Liv E. Falkenberg, René Westerhausen, Alexander R. Craven, Erik Johnsen, Rune A. Kroken, Else-Marie L⊘berg, Karsten Specht, Kenneth Hugdahl
Format:	Article
Language:	English
Published:	Elsevier 2014-01-01
Series:	NeuroImage: Clinical
Subjects:	Combined fMRI–MRS 1H-MRS Cognitive control Anterior cingulate cortex Inferior parietal lobe Glutamate BOLD Connectivity
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213158214000448

Similar Items

A pilot spectroscopy study of adversity in adolescents
by: A. Irem Sonmez, et al.
Published: (2021-12-01)

The association between language-based task-functional magnetic resonance imaging hemodynamics and baseline GABA+ and glutamate–glutamine measured in pre-supplementary motor area: A pilot study in an aging model
by: Lisa C. Krishnamurthy, et al.
Published: (2022-08-01)

Normal neurochemistry in the prefrontal and cerebellar brain of adults with attention-deficit-hyperactivity disorder
by: Dominique eEndres, et al.
Published: (2015-09-01)

Glutamate in Salience Network Predicts BOLD Response in Default Mode Network During Salience Processing
by: Felicia von Düring, et al.
Published: (2019-10-01)

GABA and glutamate in schizophrenia: A 7 T 1H-MRS study
by: Anouk Marsman, et al.
Published: (2014-01-01)

Neurochemical sex differences in adult ADHD patients: an MRS study
by: Dominique Endres, et al.
Published: (2019-10-01)

The Impact of Theta-Burst Stimulation on Cortical GABA and Glutamate in Treatment-Resistant Depression: A Surface-Based MRSI Analysis Approach
by: Benjamin Spurny-Dworak, et al.
Published: (2022-07-01)

Increased Glutamate concentrations during prolonged motor activation as measured using functional Magnetic Resonance Spectroscopy at 3T
by: Osnat Volovyk, et al.
Published: (2020-12-01)

Gamma-Aminobutyric Acid and Glutamate Concentrations in the Striatum and Anterior Cingulate Cortex Not Found to Be Associated with Cognitive Flexibility
by: Ann-Kathrin Stock, et al.
Published: (2023-08-01)

Editorial: Variability and reproducibility of brain imaging
by: Meng-Yun Wang, et al.
Published: (2024-03-01)

Fronto-striatal glutamate in children with Tourette's disorder and attention-deficit/hyperactivity disorder
by: Jilly Naaijen, et al.
Published: (2017-01-01)

Corrigendum: An fMRI study of neuronal activation in schizophrenia patients with and without previous cannabis use
by: Else-Marie eLøberg, et al.
Published: (2013-06-01)

Baseline measures of cerebral glutamate and GABA levels in individuals at ultrahigh risk for psychosis: Implications for clinical outcome after 12 months
by: C. Wenneberg, et al.
Published: (2020-01-01)

Gamma-aminobutyric acid and glutamic acid levels in the auditory pathway of rats with chronic tinnitus: A direct determination using high resolution point-resolved proton magnetic resonance spectroscopy (1H-MRS)
by: Thomas J Brozoski, et al.
Published: (2012-02-01)

Superior visual rhythm discrimination in expert musicians is most likely not related to cross-modal recruitment of the auditory cortex
by: Maksymilian Korczyk, et al.
Published: (2022-10-01)

Deep brain imaging of three participants across 1 year: The Bergen breakfast scanning club project
by: Meng-Yun Wang, et al.
Published: (2022-10-01)

Intelligence and Brain Efficiency: Investigating the Association between Working Memory Performance, Glutamate, and GABA
by: Anouk Marsman, et al.
Published: (2017-09-01)

Effects of 12-Week Methylphenidate Treatment on Neurometabolism in Adult Patients with ADHD: The First Double-Blind Placebo-Controlled MR Spectroscopy Study
by: Simon Maier, et al.
Published: (2020-08-01)

Ketamine administration in idiopathic epileptic and healthy control dogs: Can we detect differences in brain metabolite response with spectroscopy?
by: Manuela Wieser, et al.
Published: (2023-01-01)

Simultaneous quantification of GABA, Glx and GSH in the neonatal human brain using magnetic resonance spectroscopy
by: Yanez Lopez Maria, et al.
Published: (2021-06-01)

On the relationship between GABA+ and glutamate across the brain
by: Reuben Rideaux, et al.
Published: (2022-08-01)

Multinuclear Magnetic Resonance Spectroscopy at Ultra-High-Field: Assessing Human Cerebral Metabolism in Healthy and Diseased States
by: Pandichelvam Veeraiah, et al.
Published: (2023-04-01)

Magnetic resonance spectroscopy studies in migraine
by: Simona Nikolova, et al.
Published: (2022-08-01)

NEURAL CORRELATES FOR APATHY: FRONTAL - PREFRONTAL AND PARIETAL CORTICAL - SUBCORTICAL CIRCUITS
by: Rita Moretti, et al.
Published: (2016-12-01)

Multimodal assessment of the GABA system in patients with fragile-X syndrome and neurofibromatosis of type 1
by: Angelina Lacroix, et al.
Published: (2022-11-01)

Early Changes in Glutamate Metabolism and Perfusion in Basal Ganglia following Hypoxia-Ischemia in Neonatal Piglets: A Multi-Sequence 3.0T MR Study
by: Xiao-ming Wang, et al.
Published: (2017-04-01)

Treatment effects on neurometabolite levels in schizophrenia: A meta-analysis dataset of proton magnetic resonance spectroscopy
by: Manabu Kubota, et al.
Published: (2020-08-01)

Brain MR Spectroscopy in Autism Spectrum Disorder- the GABA excitatory/inhibitory imbalance theory revisited
by: Maiken Kirkegaard Brix, et al.
Published: (2015-06-01)

Risk-management at home: domestic accidents and Mrs. Henry Wood’s household advice
by: Wagner, Tamara Silvia
Published: (2022)

Functional Magnetic Resonance Spectroscopy: The “New” MRS for Cognitive Neuroscience and Psychiatry Research
by: Jeffrey A. Stanley, et al.
Published: (2018-03-01)

Sleep Apnea in Multiple System Atrophy of Cerebellar Type: A 3.0 T MRS/Volumetry Pilot Study
by: Y. Takado, et al.
Published: (2017-03-01)

No Effects of Anodal tDCS on Local GABA and Glx Levels in the Left Posterior Superior Temporal Gyrus
by: Gerard E. Dwyer, et al.
Published: (2019-01-01)

Corrigendum: M. Nygård, T. Eichele, E-M Løberg, H. A. Jørgensen, E. Johnsen, R.A. Kroken, J.Ø. Berle, K. Hugdahl: Patients with schizophrenia fail to up-regulate task-positive and down-regulate task.negative brain networks: an fMRI study using an ICA analysis approach. Frontiers in Human Neuroscience, 2012, doi: 10.3389/fnhum.2012.00149.
by: Merethe eNygård, et al.
Published: (2013-05-01)

γ-Aminobutyric acid as a biomarker of the lateralizing and monitoring drug effect in patients with magnetic resonance imaging-negative temporal lobe epilepsy
by: Shuohua Wu, et al.
Published: (2023-05-01)

Electroacupuncture ameliorate learning and memory by improving N-acetylaspartate and glutamate metabolism in APP/PS1 mice
by: Ruhui Lin, et al.
Published: (2018-07-01)

Assessment of One-year Prognosis in Patients with Stroke
by: Masoud Ghiasian, et al.
Published: (2019-01-01)

International versions of the Menopause Rating Scale (MRS)
by: Schneider Hermann PG, et al.
Published: (2003-07-01)

Assessing Metabolism and Injury in Acute Human Traumatic Brain Injury with Magnetic Resonance Spectroscopy: Current and Future Applications
by: Matthew G. Stovell, et al.
Published: (2017-09-01)

Corrigendum: Assessing Metabolism and Injury in Acute Human Traumatic Brain Injury with Magnetic Resonance Spectroscopy: Current and Future Applications
by: Matthew G. Stovell, et al.
Published: (2017-12-01)

Anterior Cingulate Cortex Glutamate Levels Are Related to Response to Initial Antipsychotic Treatment in Drug-Naive First-Episode Schizophrenia Patients
by: Jinguang Li, et al.
Published: (2020-10-01)