Overview of COVID-19’s relationship with thrombophilia proteins
COVID-19 is the most devastating pandemic situation we have experienced in our age, affecting all systems. Although it affects all systems, it shows its most important effect through thrombophilia. Therefore, the possible cause of sudden death due to COVID-19 may be embolism caused by thrombophilia....
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2021-12-01
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| Series: | Türk Biyokimya Dergisi |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/tjb-2021-0183 |
| _version_ | 1798031182260076544 |
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| author | Aydin Suna Ugur Kader Yalcin Hanifi Sahin İbrahim Akkoc Ramazan Fazil Yakar Burkay Yucel Dogan Aydin Suleyman |
| author_facet | Aydin Suna Ugur Kader Yalcin Hanifi Sahin İbrahim Akkoc Ramazan Fazil Yakar Burkay Yucel Dogan Aydin Suleyman |
| author_sort | Aydin Suna |
| collection | DOAJ |
| description | COVID-19 is the most devastating pandemic situation we have experienced in our age, affecting all systems. Although it affects all systems, it shows its most important effect through thrombophilia. Therefore, the possible cause of sudden death due to COVID-19 may be embolism caused by thrombophilia. D-dimer amounts increase due to COVID-19. The thrombosis is associated with sudden death in COVID-19 disease in populations. Since individuals with thrombophilia will be more prone to death due to COVID-19, it may be appropriate to administer low doses of Clexane (Enoxaparin sodium) or low-weight heparin for prophylactic purposes in order to consider these individuals at high risk and to prevent deaths. Moreover, in order not to risk the lives of healthcare professionals with thrombophilia, it would be appropriate to keep them away from individuals with COVID-19 disease and to employ them in different healthcare services according to their fields of expertise. It should also not be forgotten that different symptoms related to COVID-19 appear day by day, these different symptoms probably show that the virus has undergone mutations in order to survive, but no matter what, its effect on thrombophilia has not been eliminated yet. This compilation aims to present the reasons and causes of death due to COVID-19, possible treatment options, and thrombophilia panel tests and new parameters that may have a place in the meticulous interpretation of these tests and possible etiopathology in the light of current information. Therefore, presenting this information in a rational manner and keeping the parameters of the thrombophilia panel under strict control predict that the deaths due to the virus will be partially reduced. |
| first_indexed | 2024-04-11T19:53:18Z |
| format | Article |
| id | doaj.art-1dc9e11b87254108845ffb53815d29a3 |
| institution | Directory Open Access Journal |
| issn | 1303-829X |
| language | English |
| last_indexed | 2024-04-11T19:53:18Z |
| publishDate | 2021-12-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Türk Biyokimya Dergisi |
| spelling | doaj.art-1dc9e11b87254108845ffb53815d29a32022-12-22T04:06:14ZengDe GruyterTürk Biyokimya Dergisi1303-829X2021-12-0146660962210.1515/tjb-2021-0183Overview of COVID-19’s relationship with thrombophilia proteinsAydin Suna0Ugur Kader1Yalcin Hanifi2Sahin İbrahim3Akkoc Ramazan Fazil4Yakar Burkay5Yucel Dogan6Aydin Suleyman7Department of Cardiovascular Surgery, Elazig Fethi Sekin City Hospital, Health Science University, Elazig Campus, Elazig, TurkeyDepartment of Internal Medicine (Endocrinology and Metabolism Diseases), School of Medicine, Firat UniversityElazig, TurkeyDepartment of Histology and Embryology, Faculty of Veterinary Medicine, Firat UniversityElazig, TurkeyDepartment of Medical Biology, Medical School, Erzincan Binali Yildirim University, Erzincan, TurkeyDepartment of Anatomy, Medical School, Firat University, Elazig, TurkeyDepartment of Medicine, Medical School, Firat University, Elazig, TurkeyDepartment of Medical Biochemistry, Faculty of Medicine, Lokman Hekim University, Ankara, TurkeyDepartment of Medical Biochemistry and Clinical Biochemistry, (Firat Hormones Research Group), School of Medicine, Firat University, Elazig, TurkeyCOVID-19 is the most devastating pandemic situation we have experienced in our age, affecting all systems. Although it affects all systems, it shows its most important effect through thrombophilia. Therefore, the possible cause of sudden death due to COVID-19 may be embolism caused by thrombophilia. D-dimer amounts increase due to COVID-19. The thrombosis is associated with sudden death in COVID-19 disease in populations. Since individuals with thrombophilia will be more prone to death due to COVID-19, it may be appropriate to administer low doses of Clexane (Enoxaparin sodium) or low-weight heparin for prophylactic purposes in order to consider these individuals at high risk and to prevent deaths. Moreover, in order not to risk the lives of healthcare professionals with thrombophilia, it would be appropriate to keep them away from individuals with COVID-19 disease and to employ them in different healthcare services according to their fields of expertise. It should also not be forgotten that different symptoms related to COVID-19 appear day by day, these different symptoms probably show that the virus has undergone mutations in order to survive, but no matter what, its effect on thrombophilia has not been eliminated yet. This compilation aims to present the reasons and causes of death due to COVID-19, possible treatment options, and thrombophilia panel tests and new parameters that may have a place in the meticulous interpretation of these tests and possible etiopathology in the light of current information. Therefore, presenting this information in a rational manner and keeping the parameters of the thrombophilia panel under strict control predict that the deaths due to the virus will be partially reduced.https://doi.org/10.1515/tjb-2021-0183anticoagulantcovid-19thrombophiliathrombosis |
| spellingShingle | Aydin Suna Ugur Kader Yalcin Hanifi Sahin İbrahim Akkoc Ramazan Fazil Yakar Burkay Yucel Dogan Aydin Suleyman Overview of COVID-19’s relationship with thrombophilia proteins Türk Biyokimya Dergisi anticoagulant covid-19 thrombophilia thrombosis |
| title | Overview of COVID-19’s relationship with thrombophilia proteins |
| title_full | Overview of COVID-19’s relationship with thrombophilia proteins |
| title_fullStr | Overview of COVID-19’s relationship with thrombophilia proteins |
| title_full_unstemmed | Overview of COVID-19’s relationship with thrombophilia proteins |
| title_short | Overview of COVID-19’s relationship with thrombophilia proteins |
| title_sort | overview of covid 19 s relationship with thrombophilia proteins |
| topic | anticoagulant covid-19 thrombophilia thrombosis |
| url | https://doi.org/10.1515/tjb-2021-0183 |
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