Primary intra- and extradural extramedullary mesenchymal chondrosarcoma with isolated punctate calcification: case report and literature review
Abstract Background Mesenchymal chondrosarcoma (MCS) is an ultra-rare, high-grade subtype of chondrosarcoma affecting both bone and soft tissues. Extra-skeletal MCS rarely occurs in intra- and extradural regions. Case presentation We presented a case of intraspinal dumbbell-shaped MCS at the T12-L2...
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| Format: | Article |
| Language: | English |
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BMC
2022-03-01
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| Series: | BMC Neurology |
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| Online Access: | https://doi.org/10.1186/s12883-022-02645-x |
| _version_ | 1818358462665457664 |
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| author | Meigui Chen Qingquan Lai |
| author_facet | Meigui Chen Qingquan Lai |
| author_sort | Meigui Chen |
| collection | DOAJ |
| description | Abstract Background Mesenchymal chondrosarcoma (MCS) is an ultra-rare, high-grade subtype of chondrosarcoma affecting both bone and soft tissues. Extra-skeletal MCS rarely occurs in intra- and extradural regions. Case presentation We presented a case of intraspinal dumbbell-shaped MCS at the T12-L2 level with isolated punctate calcification in a 19-year-old male complaining of progressive lower back pain. Surgical treatment for removal of the tumor was performed. The postoperative pathological result confirmed MCS. The patient showed symptomatic improvement and follow-up MRI showed no evidence of recurrence or metastasis for nearly 1 year after surgery. Conclusions CT and MRI play an important role in differential diagnosis for intraspinal MCS. MCS should be added to the differential diagnosis of intraspinal dumbbell-shaped tumors, especially when radiological examinations reveal punctate calcification in a homogeneous enhanced tumor without dural tail sign. However, the final diagnosis depends on histopathological results. Despite the good prognosis of intraspinal MCS, close follow-up after operation is still necessary. |
| first_indexed | 2024-12-13T20:29:23Z |
| format | Article |
| id | doaj.art-1dce1bbf436240c5b12e4873e6a5049e |
| institution | Directory Open Access Journal |
| issn | 1471-2377 |
| language | English |
| last_indexed | 2024-12-13T20:29:23Z |
| publishDate | 2022-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Neurology |
| spelling | doaj.art-1dce1bbf436240c5b12e4873e6a5049e2022-12-21T23:32:28ZengBMCBMC Neurology1471-23772022-03-012211610.1186/s12883-022-02645-xPrimary intra- and extradural extramedullary mesenchymal chondrosarcoma with isolated punctate calcification: case report and literature reviewMeigui Chen0Qingquan Lai1Department of Radiology, The Second Affiliated Hospital of Fujian Medical UniversityDepartment of Radiology, The Second Affiliated Hospital of Fujian Medical UniversityAbstract Background Mesenchymal chondrosarcoma (MCS) is an ultra-rare, high-grade subtype of chondrosarcoma affecting both bone and soft tissues. Extra-skeletal MCS rarely occurs in intra- and extradural regions. Case presentation We presented a case of intraspinal dumbbell-shaped MCS at the T12-L2 level with isolated punctate calcification in a 19-year-old male complaining of progressive lower back pain. Surgical treatment for removal of the tumor was performed. The postoperative pathological result confirmed MCS. The patient showed symptomatic improvement and follow-up MRI showed no evidence of recurrence or metastasis for nearly 1 year after surgery. Conclusions CT and MRI play an important role in differential diagnosis for intraspinal MCS. MCS should be added to the differential diagnosis of intraspinal dumbbell-shaped tumors, especially when radiological examinations reveal punctate calcification in a homogeneous enhanced tumor without dural tail sign. However, the final diagnosis depends on histopathological results. Despite the good prognosis of intraspinal MCS, close follow-up after operation is still necessary.https://doi.org/10.1186/s12883-022-02645-xCase report, Mesenchymal chondrosarcoma, intra- and extraduralDumbbell-shapeCalcification |
| spellingShingle | Meigui Chen Qingquan Lai Primary intra- and extradural extramedullary mesenchymal chondrosarcoma with isolated punctate calcification: case report and literature review BMC Neurology Case report, Mesenchymal chondrosarcoma, intra- and extradural Dumbbell-shape Calcification |
| title | Primary intra- and extradural extramedullary mesenchymal chondrosarcoma with isolated punctate calcification: case report and literature review |
| title_full | Primary intra- and extradural extramedullary mesenchymal chondrosarcoma with isolated punctate calcification: case report and literature review |
| title_fullStr | Primary intra- and extradural extramedullary mesenchymal chondrosarcoma with isolated punctate calcification: case report and literature review |
| title_full_unstemmed | Primary intra- and extradural extramedullary mesenchymal chondrosarcoma with isolated punctate calcification: case report and literature review |
| title_short | Primary intra- and extradural extramedullary mesenchymal chondrosarcoma with isolated punctate calcification: case report and literature review |
| title_sort | primary intra and extradural extramedullary mesenchymal chondrosarcoma with isolated punctate calcification case report and literature review |
| topic | Case report, Mesenchymal chondrosarcoma, intra- and extradural Dumbbell-shape Calcification |
| url | https://doi.org/10.1186/s12883-022-02645-x |
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