Cheminformatics Identification and Validation of Dipeptidyl Peptidase-IV Modulators from Shikimate Pathway-Derived Phenolic Acids towards Interventive Type-2 Diabetes Therapy

Cheminformatics Identification and Validation of Dipeptidyl Peptidase-IV Modulators from Shikimate Pathway-Derived Phenolic Acids towards Interventive Type-2 Diabetes Therapy

Recently, dipeptidyl peptidase-IV (DPP-IV) has become an effective target in the management of type-2 diabetes mellitus (T2D). The study aimed to determine the efficacy of shikimate pathway-derived phenolic acids as potential DPP-IV modulators in the management of T2D. The study explored in silico (...

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Bibliographic Details
Main Authors: Fatai Oladunni Balogun, Kaylene Naidoo, Jamiu Olaseni Aribisala, Charlene Pillay, Saheed Sabiu
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Metabolites
Subjects:
chlorogenic acid
diprotin A
dipeptidyl peptidase IV
molecular dynamics simulations
phenolic acids
type-2 diabetes mellitus
Online Access:https://www.mdpi.com/2218-1989/12/10/937

Internet

https://www.mdpi.com/2218-1989/12/10/937

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