Severe hypercalcemia as a result of disseminated Candida krusei infection
Candida krusei disseminated infection is a rare complication of protracted neutropenia. Herein, we report a case of a 31-year-old male with relapsed acute myeloid leukemia who developed Candida krusei fungemia with cutaneous, ocular, splenic, renal, bone marrow and osseous involvement leading to sev...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-03-01
|
| Series: | International Journal of Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971224000134 |
| _version_ | 1827346871315595264 |
|---|---|
| author | Amenah Alghamdi Torrance Oravec Cesilia Nishi Eric Eckbo Krista Marcon Alissa Wright Allison Mah Jennifer White Tom Nevill Sara Belga |
| author_facet | Amenah Alghamdi Torrance Oravec Cesilia Nishi Eric Eckbo Krista Marcon Alissa Wright Allison Mah Jennifer White Tom Nevill Sara Belga |
| author_sort | Amenah Alghamdi |
| collection | DOAJ |
| description | Candida krusei disseminated infection is a rare complication of protracted neutropenia. Herein, we report a case of a 31-year-old male with relapsed acute myeloid leukemia who developed Candida krusei fungemia with cutaneous, ocular, splenic, renal, bone marrow and osseous involvement leading to severe hypercalcemia, treated with parenteral antifungals followed by oral ibrexafungerp. |
| first_indexed | 2024-03-07T23:39:02Z |
| format | Article |
| id | doaj.art-1dd1f0858ea74152b8cb6d3231b34b6e |
| institution | Directory Open Access Journal |
| issn | 1201-9712 |
| language | English |
| last_indexed | 2024-03-07T23:39:02Z |
| publishDate | 2024-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Infectious Diseases |
| spelling | doaj.art-1dd1f0858ea74152b8cb6d3231b34b6e2024-02-20T04:18:55ZengElsevierInternational Journal of Infectious Diseases1201-97122024-03-01140110112Severe hypercalcemia as a result of disseminated Candida krusei infectionAmenah Alghamdi0Torrance Oravec1Cesilia Nishi2Eric Eckbo3Krista Marcon4Alissa Wright5Allison Mah6Jennifer White7Tom Nevill8Sara Belga9Department of Medicine, Division of Infectious Diseases, University of British Columbia, Vancouver, Canada; Department of Medicine, Division of Infectious Diseases, King Abdulaziz University, Jeddah, Saudi Arabia; Corresponding author:Department of Medicine, Division of Infectious Diseases, University of British Columbia, Vancouver, CanadaDepartment of Medicine, Division of Infectious Diseases, University of British Columbia, Vancouver, Canada; Department of Pharmaceutical Sciences, Vancouver General Hospital, Vancouver, Canada; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, CanadaDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada; Department of Pathology and Laboratory Medicine, Vancouver Coastal Health, Vancouver, CanadaDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada; Department of Pathology and Laboratory Medicine, Vancouver Coastal Health, Vancouver, CanadaDepartment of Medicine, Division of Infectious Diseases, University of British Columbia, Vancouver, CanadaDepartment of Medicine, Division of Infectious Diseases, University of British Columbia, Vancouver, CanadaLeukemia Bone Marrow Transplant Program of BC, British Columbia Cancer Agency, Vancouver, Canada; Department of Medicine, Division of Hematology, University of British Columbia, Vancouver, CanadaLeukemia Bone Marrow Transplant Program of BC, British Columbia Cancer Agency, Vancouver, Canada; Department of Medicine, Division of Hematology, University of British Columbia, Vancouver, CanadaDepartment of Medicine, Division of Infectious Diseases, University of British Columbia, Vancouver, Canada; Vancouver Coastal Health Research Institute, Vancouver, CanadaCandida krusei disseminated infection is a rare complication of protracted neutropenia. Herein, we report a case of a 31-year-old male with relapsed acute myeloid leukemia who developed Candida krusei fungemia with cutaneous, ocular, splenic, renal, bone marrow and osseous involvement leading to severe hypercalcemia, treated with parenteral antifungals followed by oral ibrexafungerp.http://www.sciencedirect.com/science/article/pii/S1201971224000134Candida kruseiPichia kudriavzeviiHypercalcemiaInvasive candidiasis |
| spellingShingle | Amenah Alghamdi Torrance Oravec Cesilia Nishi Eric Eckbo Krista Marcon Alissa Wright Allison Mah Jennifer White Tom Nevill Sara Belga Severe hypercalcemia as a result of disseminated Candida krusei infection International Journal of Infectious Diseases Candida krusei Pichia kudriavzevii Hypercalcemia Invasive candidiasis |
| title | Severe hypercalcemia as a result of disseminated Candida krusei infection |
| title_full | Severe hypercalcemia as a result of disseminated Candida krusei infection |
| title_fullStr | Severe hypercalcemia as a result of disseminated Candida krusei infection |
| title_full_unstemmed | Severe hypercalcemia as a result of disseminated Candida krusei infection |
| title_short | Severe hypercalcemia as a result of disseminated Candida krusei infection |
| title_sort | severe hypercalcemia as a result of disseminated candida krusei infection |
| topic | Candida krusei Pichia kudriavzevii Hypercalcemia Invasive candidiasis |
| url | http://www.sciencedirect.com/science/article/pii/S1201971224000134 |
| work_keys_str_mv | AT amenahalghamdi severehypercalcemiaasaresultofdisseminatedcandidakruseiinfection AT torranceoravec severehypercalcemiaasaresultofdisseminatedcandidakruseiinfection AT cesilianishi severehypercalcemiaasaresultofdisseminatedcandidakruseiinfection AT ericeckbo severehypercalcemiaasaresultofdisseminatedcandidakruseiinfection AT kristamarcon severehypercalcemiaasaresultofdisseminatedcandidakruseiinfection AT alissawright severehypercalcemiaasaresultofdisseminatedcandidakruseiinfection AT allisonmah severehypercalcemiaasaresultofdisseminatedcandidakruseiinfection AT jenniferwhite severehypercalcemiaasaresultofdisseminatedcandidakruseiinfection AT tomnevill severehypercalcemiaasaresultofdisseminatedcandidakruseiinfection AT sarabelga severehypercalcemiaasaresultofdisseminatedcandidakruseiinfection |