HIV-Infected Spleens Present Altered Follicular Helper T Cell (Tfh) Subsets and Skewed B Cell Maturation.

HIV-Infected Spleens Present Altered Follicular Helper T Cell (Tfh) Subsets and Skewed B Cell Maturation.

Follicular helper T (Tfh) cells within secondary lymphoid organs control multiple steps of B cell maturation and antibody (Ab) production. HIV-1 infection is associated with an altered B cell differentiation and Tfh isolated from lymph nodes of HIV-infected (HIV+) individuals provide inadequate B ce...

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Bibliographic Details
Main Authors: Lucie Colineau, Angeline Rouers, Takuya Yamamoto, Yin Xu, Alejandra Urrutia, Hang-Phuong Pham, Sylvain Cardinaud, Assia Samri, Karim Dorgham, Pierre-Grégoire Coulon, Rémi Cheynier, Anne Hosmalin, Eric Oksenhendler, Adrien Six, Anthony D Kelleher, John Zaunders, Richard A Koup, Brigitte Autran, Arnaud Moris, Stéphanie Graff-Dubois
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4621058?pdf=render

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