Carp proteins as a source of bioactive peptides - an in silico approach
In silico prediction methods and tools were used to determine whether bioactive peptides are hidden in the amino acid sequences of carp (Cyprinus carpio) proteins and whether they can be released after gastric, duodenal, and gastro-duodenal in silico digestion. Fragments with 15 types of biological...
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| Format: | Article |
| Language: | English |
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Czech Academy of Agricultural Sciences
2016-04-01
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| Series: | Czech Journal of Food Sciences |
| Subjects: | |
| Online Access: | https://cjfs.agriculturejournals.cz/artkey/cjf-201602-0003_carp-proteins-as-a-source-of-bioactive-peptides-an-in-silico-approach.php |
| _version_ | 1797899655875395584 |
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| author | Małgorzata Darewicz Justyna Borawska Monika Pliszka |
| author_facet | Małgorzata Darewicz Justyna Borawska Monika Pliszka |
| author_sort | Małgorzata Darewicz |
| collection | DOAJ |
| description | In silico prediction methods and tools were used to determine whether bioactive peptides are hidden in the amino acid sequences of carp (Cyprinus carpio) proteins and whether they can be released after gastric, duodenal, and gastro-duodenal in silico digestion. Fragments with 15 types of biological activity in intact proteins and, after gastrointestinal digestion, with 11 types of activity were identified. Angiotensin I-converting enzyme inhibitory (ACEi) and antioxidant peptides were the most predominant fragments of proteins in the group of intact proteins and in silico digests. After in silico digestion the highest number of sequences with ACEi activity (108) and antioxidant activity (13) was released after gastro-duodenal digestion of the myosin heavy chain. |
| first_indexed | 2024-04-10T08:32:23Z |
| format | Article |
| id | doaj.art-1dd9ad6224e44c46b6db96b212ce209a |
| institution | Directory Open Access Journal |
| issn | 1212-1800 1805-9317 |
| language | English |
| last_indexed | 2024-04-10T08:32:23Z |
| publishDate | 2016-04-01 |
| publisher | Czech Academy of Agricultural Sciences |
| record_format | Article |
| series | Czech Journal of Food Sciences |
| spelling | doaj.art-1dd9ad6224e44c46b6db96b212ce209a2023-02-23T03:28:19ZengCzech Academy of Agricultural SciencesCzech Journal of Food Sciences1212-18001805-93172016-04-0134211111710.17221/300/2015-CJFScjf-201602-0003Carp proteins as a source of bioactive peptides - an in silico approachMałgorzata Darewicz0Justyna Borawska1Monika Pliszka2Department of Food Biochemistry, Faculty of Food Science, University of Warmia and Mazury in Olsztyn, Olsztyn, PolandDepartment of Food Biochemistry, Faculty of Food Science, University of Warmia and Mazury in Olsztyn, Olsztyn, PolandDepartment of Food Biochemistry, Faculty of Food Science, University of Warmia and Mazury in Olsztyn, Olsztyn, PolandIn silico prediction methods and tools were used to determine whether bioactive peptides are hidden in the amino acid sequences of carp (Cyprinus carpio) proteins and whether they can be released after gastric, duodenal, and gastro-duodenal in silico digestion. Fragments with 15 types of biological activity in intact proteins and, after gastrointestinal digestion, with 11 types of activity were identified. Angiotensin I-converting enzyme inhibitory (ACEi) and antioxidant peptides were the most predominant fragments of proteins in the group of intact proteins and in silico digests. After in silico digestion the highest number of sequences with ACEi activity (108) and antioxidant activity (13) was released after gastro-duodenal digestion of the myosin heavy chain.https://cjfs.agriculturejournals.cz/artkey/cjf-201602-0003_carp-proteins-as-a-source-of-bioactive-peptides-an-in-silico-approach.phpbiological activitybioinformaticsbiopepfishdatabasesproteolysis |
| spellingShingle | Małgorzata Darewicz Justyna Borawska Monika Pliszka Carp proteins as a source of bioactive peptides - an in silico approach Czech Journal of Food Sciences biological activity bioinformatics biopep fish databases proteolysis |
| title | Carp proteins as a source of bioactive peptides - an in silico approach |
| title_full | Carp proteins as a source of bioactive peptides - an in silico approach |
| title_fullStr | Carp proteins as a source of bioactive peptides - an in silico approach |
| title_full_unstemmed | Carp proteins as a source of bioactive peptides - an in silico approach |
| title_short | Carp proteins as a source of bioactive peptides - an in silico approach |
| title_sort | carp proteins as a source of bioactive peptides an in silico approach |
| topic | biological activity bioinformatics biopep fish databases proteolysis |
| url | https://cjfs.agriculturejournals.cz/artkey/cjf-201602-0003_carp-proteins-as-a-source-of-bioactive-peptides-an-in-silico-approach.php |
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