Ball Milling Promoted N-Heterocycles Synthesis

In the last years, numerous protocols have been published using ball milling for organic synthesis. Compared to other methods such as microwave or ultrasound irradiation and ionic liquids, ball mill chemistry is an economical, and ecofriendly method in organic synthesis that is rather underrepresent...

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Main Authors: Taghreed H. El-Sayed, Asmaa Aboelnaga, Mohamed A. El-Atawy, Mohamed Hagar
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/23/6/1348
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author Taghreed H. El-Sayed
Asmaa Aboelnaga
Mohamed A. El-Atawy
Mohamed Hagar
author_facet Taghreed H. El-Sayed
Asmaa Aboelnaga
Mohamed A. El-Atawy
Mohamed Hagar
author_sort Taghreed H. El-Sayed
collection DOAJ
description In the last years, numerous protocols have been published using ball milling for organic synthesis. Compared to other methods such as microwave or ultrasound irradiation and ionic liquids, ball mill chemistry is an economical, and ecofriendly method in organic synthesis that is rather underrepresented in the knowledge of organic chemists. The aim of this review is to explore the advantages of the application of ball milling in synthesis of N-heterocyclic compounds.
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spelling doaj.art-1dda2a12c3b94685be9df58e7f11e4912022-12-22T00:52:51ZengMDPI AGMolecules1420-30492018-06-01236134810.3390/molecules23061348molecules23061348Ball Milling Promoted N-Heterocycles SynthesisTaghreed H. El-Sayed0Asmaa Aboelnaga1Mohamed A. El-Atawy2Mohamed Hagar3Chemistry Department, Faculty of Science, Taibah University, Yanbu 46423 Saudi ArabiaChemistry Department, Faculty of Science, Taibah University, Yanbu 46423 Saudi ArabiaChemistry Department, Faculty of Science, Taibah University, Yanbu 46423 Saudi ArabiaChemistry Department, Faculty of Science, Taibah University, Yanbu 46423 Saudi ArabiaIn the last years, numerous protocols have been published using ball milling for organic synthesis. Compared to other methods such as microwave or ultrasound irradiation and ionic liquids, ball mill chemistry is an economical, and ecofriendly method in organic synthesis that is rather underrepresented in the knowledge of organic chemists. The aim of this review is to explore the advantages of the application of ball milling in synthesis of N-heterocyclic compounds.http://www.mdpi.com/1420-3049/23/6/1348ball millinggreen synthesismechanochemistryN-heterocycles
spellingShingle Taghreed H. El-Sayed
Asmaa Aboelnaga
Mohamed A. El-Atawy
Mohamed Hagar
Ball Milling Promoted N-Heterocycles Synthesis
Molecules
ball milling
green synthesis
mechanochemistry
N-heterocycles
title Ball Milling Promoted N-Heterocycles Synthesis
title_full Ball Milling Promoted N-Heterocycles Synthesis
title_fullStr Ball Milling Promoted N-Heterocycles Synthesis
title_full_unstemmed Ball Milling Promoted N-Heterocycles Synthesis
title_short Ball Milling Promoted N-Heterocycles Synthesis
title_sort ball milling promoted n heterocycles synthesis
topic ball milling
green synthesis
mechanochemistry
N-heterocycles
url http://www.mdpi.com/1420-3049/23/6/1348
work_keys_str_mv AT taghreedhelsayed ballmillingpromotednheterocyclessynthesis
AT asmaaaboelnaga ballmillingpromotednheterocyclessynthesis
AT mohamedaelatawy ballmillingpromotednheterocyclessynthesis
AT mohamedhagar ballmillingpromotednheterocyclessynthesis