Pro-Inflammatory Effects of NX-3 Toxin Are Comparable to Deoxynivalenol and not Modulated by the Co-Occurring Pro-Oxidant Aurofusarin

Pro-Inflammatory Effects of NX-3 Toxin Are Comparable to Deoxynivalenol and not Modulated by the Co-Occurring Pro-Oxidant Aurofusarin

The type A trichothecene NX-3, produced by certain <i>Fusarium graminearum</i> strains, is similar to the mycotoxin deoxynivalenol (DON), with the exception that it lacks the carbonyl moiety at the C-8 position. NX-3 inhibits protein biosynthesis and induces cytotoxicity to a similar ext...

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Bibliographic Details
Main Authors: Lydia Woelflingseder, Nadia Gruber, Gerhard Adam, Doris Marko
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Microorganisms
Subjects:
mycotoxin
trichothecene
NF-κB
intestinal inflammation
combinatory effects
food safety
Online Access:https://www.mdpi.com/2076-2607/8/4/603

Internet

https://www.mdpi.com/2076-2607/8/4/603

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