Twenty-two years of dengue outbreaks in Bangladesh: epidemiology, clinical spectrum, serotypes, and future disease risks
Abstract Dengue is the most rapidly spreading mosquito-borne disease and has become a major public health threat, particularly for tropical and subtropical countries including Bangladesh. This comprehensive review aims to summarize the overall scenario of dengue, including disease burden, clinical s...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-07-01
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| Series: | Tropical Medicine and Health |
| Online Access: | https://doi.org/10.1186/s41182-023-00528-6 |
| _version_ | 1797778682327072768 |
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| author | Mohammad Sorowar Hossain Abdullah Al Noman SM Abdullah Al Mamun Abdullah Al Mosabbir |
| author_facet | Mohammad Sorowar Hossain Abdullah Al Noman SM Abdullah Al Mamun Abdullah Al Mosabbir |
| author_sort | Mohammad Sorowar Hossain |
| collection | DOAJ |
| description | Abstract Dengue is the most rapidly spreading mosquito-borne disease and has become a major public health threat, particularly for tropical and subtropical countries including Bangladesh. This comprehensive review aims to summarize the overall scenario of dengue, including disease burden, clinical spectrum, seroprevalence, circulating serotypes/genotypes, and spatial distribution since the first recorded outbreak in Bangladesh. Since the first recorded outbreak in 2000, dengue epidemiology has shown the typical epidemic pattern with more frequent and bigger outbreaks and gradual geographic expansion to non-endemic regions in Bangladesh. For instance, highly confined Rohingya refugee camps that provide shelters to nearly 1.2 million forcibly displaced vulnerable Myanmar nationals in Cox’s Bazar district confronted a massive outbreak in 2022. Recent major outbreaks are found to be associated with the emergence of serotype DENV-3, which was undetected for a long time. Consequently, changes in serotypes might be attributed to increased severity in clinical manifestation in recent years. The existing weak surveillance and risk management systems are inadequate to deal with impending dengue risks. The healthcare system, particularly at the district level, is not prepared to manage impending large-scale dengue outbreaks in Bangladesh. Our findings would contribute to the development of strategies for dengue control and management in Bangladesh as well as other similar settings elsewhere in the world. |
| first_indexed | 2024-03-12T23:20:02Z |
| format | Article |
| id | doaj.art-1de444dac1a7467187e98c2ccd2bc87f |
| institution | Directory Open Access Journal |
| issn | 1349-4147 |
| language | English |
| last_indexed | 2024-03-12T23:20:02Z |
| publishDate | 2023-07-01 |
| publisher | BMC |
| record_format | Article |
| series | Tropical Medicine and Health |
| spelling | doaj.art-1de444dac1a7467187e98c2ccd2bc87f2023-07-16T11:28:24ZengBMCTropical Medicine and Health1349-41472023-07-0151111410.1186/s41182-023-00528-6Twenty-two years of dengue outbreaks in Bangladesh: epidemiology, clinical spectrum, serotypes, and future disease risksMohammad Sorowar Hossain0Abdullah Al Noman1SM Abdullah Al Mamun2Abdullah Al Mosabbir3Department of Emerging and Neglected Diseases, Biomedical Research FoundationDepartment of Emerging and Neglected Diseases, Biomedical Research FoundationDepartment of Emerging and Neglected Diseases, Biomedical Research FoundationDepartment of Emerging and Neglected Diseases, Biomedical Research FoundationAbstract Dengue is the most rapidly spreading mosquito-borne disease and has become a major public health threat, particularly for tropical and subtropical countries including Bangladesh. This comprehensive review aims to summarize the overall scenario of dengue, including disease burden, clinical spectrum, seroprevalence, circulating serotypes/genotypes, and spatial distribution since the first recorded outbreak in Bangladesh. Since the first recorded outbreak in 2000, dengue epidemiology has shown the typical epidemic pattern with more frequent and bigger outbreaks and gradual geographic expansion to non-endemic regions in Bangladesh. For instance, highly confined Rohingya refugee camps that provide shelters to nearly 1.2 million forcibly displaced vulnerable Myanmar nationals in Cox’s Bazar district confronted a massive outbreak in 2022. Recent major outbreaks are found to be associated with the emergence of serotype DENV-3, which was undetected for a long time. Consequently, changes in serotypes might be attributed to increased severity in clinical manifestation in recent years. The existing weak surveillance and risk management systems are inadequate to deal with impending dengue risks. The healthcare system, particularly at the district level, is not prepared to manage impending large-scale dengue outbreaks in Bangladesh. Our findings would contribute to the development of strategies for dengue control and management in Bangladesh as well as other similar settings elsewhere in the world.https://doi.org/10.1186/s41182-023-00528-6 |
| spellingShingle | Mohammad Sorowar Hossain Abdullah Al Noman SM Abdullah Al Mamun Abdullah Al Mosabbir Twenty-two years of dengue outbreaks in Bangladesh: epidemiology, clinical spectrum, serotypes, and future disease risks Tropical Medicine and Health |
| title | Twenty-two years of dengue outbreaks in Bangladesh: epidemiology, clinical spectrum, serotypes, and future disease risks |
| title_full | Twenty-two years of dengue outbreaks in Bangladesh: epidemiology, clinical spectrum, serotypes, and future disease risks |
| title_fullStr | Twenty-two years of dengue outbreaks in Bangladesh: epidemiology, clinical spectrum, serotypes, and future disease risks |
| title_full_unstemmed | Twenty-two years of dengue outbreaks in Bangladesh: epidemiology, clinical spectrum, serotypes, and future disease risks |
| title_short | Twenty-two years of dengue outbreaks in Bangladesh: epidemiology, clinical spectrum, serotypes, and future disease risks |
| title_sort | twenty two years of dengue outbreaks in bangladesh epidemiology clinical spectrum serotypes and future disease risks |
| url | https://doi.org/10.1186/s41182-023-00528-6 |
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