Summer fades, deer change: Photoperiodic control of cellular seasonal acclimatization of skeletal muscle
Summary: We found major seasonal changes of polyunsaturated fatty acids (PUFAs) in muscular phospholipids (PL) in a large non-hibernating mammal, the red deer (Cervus elaphus). Dietary supply of essential linoleic acid (LA) and α-linolenic acid (ALA) had no, or only weak influence, respectively. We...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-01-01
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| Series: | iScience |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004223026962 |
| _version_ | 1797383734817718272 |
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| author | Kristina Gasch Alba Hykollari Manuela Habe Patricia Haubensak Johanna Painer-Gigler Steve Smith Gabrielle Stalder Walter Arnold |
| author_facet | Kristina Gasch Alba Hykollari Manuela Habe Patricia Haubensak Johanna Painer-Gigler Steve Smith Gabrielle Stalder Walter Arnold |
| author_sort | Kristina Gasch |
| collection | DOAJ |
| description | Summary: We found major seasonal changes of polyunsaturated fatty acids (PUFAs) in muscular phospholipids (PL) in a large non-hibernating mammal, the red deer (Cervus elaphus). Dietary supply of essential linoleic acid (LA) and α-linolenic acid (ALA) had no, or only weak influence, respectively. We further found correlations of PL PUFA concentrations with the activity of key metabolic enzymes, independent of higher winter expression. Activity of the sarcoplasmic reticulum (SR) Ca++-ATPase increased with SR PL concentrations of n-6 PUFA, and of cytochrome c oxidase and citrate synthase, indicators of ATP-production, with concentrations of eicosapentaenoic acid in mitochondrial PL. All detected cyclic molecular changes were controlled by photoperiod and are likely of general relevance for mammals living in seasonal environments, including humans. During winter, these changes at the molecular level presumably compensate for Arrhenius effects in the colder peripheral body parts and thus enable a thrifty life at lower body temperature. |
| first_indexed | 2024-03-08T21:24:55Z |
| format | Article |
| id | doaj.art-1ded599a9b0b4172b1843f9ff7151bdd |
| institution | Directory Open Access Journal |
| issn | 2589-0042 |
| language | English |
| last_indexed | 2024-03-08T21:24:55Z |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | iScience |
| spelling | doaj.art-1ded599a9b0b4172b1843f9ff7151bdd2023-12-21T07:36:17ZengElsevieriScience2589-00422024-01-01271108619Summer fades, deer change: Photoperiodic control of cellular seasonal acclimatization of skeletal muscleKristina Gasch0Alba Hykollari1Manuela Habe2Patricia Haubensak3Johanna Painer-Gigler4Steve Smith5Gabrielle Stalder6Walter Arnold7Research Institute of Wildlife Ecology, Department of Interdisciplinary Life Science, University of Veterinary Medicine Vienna, 1160 Vienna, AustriaResearch Institute of Wildlife Ecology, Department of Interdisciplinary Life Science, University of Veterinary Medicine Vienna, 1160 Vienna, AustriaResearch Institute of Wildlife Ecology, Department of Interdisciplinary Life Science, University of Veterinary Medicine Vienna, 1160 Vienna, AustriaKonrad Lorenz Institute of Ethology, Department of Interdisciplinary Life Science, University of Veterinary Medicine Vienna, 1160 Vienna, AustriaResearch Institute of Wildlife Ecology, Department of Interdisciplinary Life Science, University of Veterinary Medicine Vienna, 1160 Vienna, AustriaKonrad Lorenz Institute of Ethology, Department of Interdisciplinary Life Science, University of Veterinary Medicine Vienna, 1160 Vienna, AustriaResearch Institute of Wildlife Ecology, Department of Interdisciplinary Life Science, University of Veterinary Medicine Vienna, 1160 Vienna, AustriaResearch Institute of Wildlife Ecology, Department of Interdisciplinary Life Science, University of Veterinary Medicine Vienna, 1160 Vienna, Austria; Corresponding authorSummary: We found major seasonal changes of polyunsaturated fatty acids (PUFAs) in muscular phospholipids (PL) in a large non-hibernating mammal, the red deer (Cervus elaphus). Dietary supply of essential linoleic acid (LA) and α-linolenic acid (ALA) had no, or only weak influence, respectively. We further found correlations of PL PUFA concentrations with the activity of key metabolic enzymes, independent of higher winter expression. Activity of the sarcoplasmic reticulum (SR) Ca++-ATPase increased with SR PL concentrations of n-6 PUFA, and of cytochrome c oxidase and citrate synthase, indicators of ATP-production, with concentrations of eicosapentaenoic acid in mitochondrial PL. All detected cyclic molecular changes were controlled by photoperiod and are likely of general relevance for mammals living in seasonal environments, including humans. During winter, these changes at the molecular level presumably compensate for Arrhenius effects in the colder peripheral body parts and thus enable a thrifty life at lower body temperature.http://www.sciencedirect.com/science/article/pii/S2589004223026962ZoologyEvolutionary biologyAnimal physiology |
| spellingShingle | Kristina Gasch Alba Hykollari Manuela Habe Patricia Haubensak Johanna Painer-Gigler Steve Smith Gabrielle Stalder Walter Arnold Summer fades, deer change: Photoperiodic control of cellular seasonal acclimatization of skeletal muscle iScience Zoology Evolutionary biology Animal physiology |
| title | Summer fades, deer change: Photoperiodic control of cellular seasonal acclimatization of skeletal muscle |
| title_full | Summer fades, deer change: Photoperiodic control of cellular seasonal acclimatization of skeletal muscle |
| title_fullStr | Summer fades, deer change: Photoperiodic control of cellular seasonal acclimatization of skeletal muscle |
| title_full_unstemmed | Summer fades, deer change: Photoperiodic control of cellular seasonal acclimatization of skeletal muscle |
| title_short | Summer fades, deer change: Photoperiodic control of cellular seasonal acclimatization of skeletal muscle |
| title_sort | summer fades deer change photoperiodic control of cellular seasonal acclimatization of skeletal muscle |
| topic | Zoology Evolutionary biology Animal physiology |
| url | http://www.sciencedirect.com/science/article/pii/S2589004223026962 |
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