Nociceptin/Orphanin FQ receptor expression in primary human umbilical vein endothelial cells is not regulated by exposure to breast cancer cell media or angiogenic stimuli

Nociceptin/Orphanin FQ receptor expression in primary human umbilical vein endothelial cells is not regulated by exposure to breast cancer cell media or angiogenic stimuli

Background: Opioid receptors are naloxone-sensitive (MOP [mu: μ], DOP [delta: δ], and KOP [kappa: κ]) and naloxone-insensitive Nociceptin/Orphanin FQ (N/OFQ) peptide receptor (NOP). Clinically, most opioid analgesics target MOP. Angiogenesis is the formation of new blood vessels and involves endothe...

Full description

Bibliographic Details
Main Authors: Despina Giakomidi, Sonja Khemiri, Wadhah Mahbuba, David G. McVey, Fatin Al-Janabi, Remo Guerrini, Girolamo Calo, Shu Ye, David G. Lambert
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:BJA Open
Subjects:
angiogenesis
cancer
confocal microscopy
HUVE cells
nociceptin/orphanin FQ receptors (NOP)
Online Access:http://www.sciencedirect.com/science/article/pii/S2772609622001095

Similar Items

Similar Items