A new semi-quantitative Surface-Enhanced Raman Spectroscopy (SERS) method for detection of maleimide (2,5-pyrroledione) with potential application to astrobiology
Nitrogen-containing heterocyclic compounds are fundamental biochemical components of all life on Earth and, presumably, life elsewhere in our solar system. Detection and characterization of these compounds by traditional solvent extraction, chromatographic separation, and GC–MS analysis require more...
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| Format: | Article |
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Elsevier
2021-09-01
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| Series: | Geoscience Frontiers |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1674987121000906 |
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| author | J. Aramendia L. Gomez-Nubla M.L. Tuite K.H. Williford K. Castro J.M. Madariaga |
| author_facet | J. Aramendia L. Gomez-Nubla M.L. Tuite K.H. Williford K. Castro J.M. Madariaga |
| author_sort | J. Aramendia |
| collection | DOAJ |
| description | Nitrogen-containing heterocyclic compounds are fundamental biochemical components of all life on Earth and, presumably, life elsewhere in our solar system. Detection and characterization of these compounds by traditional solvent extraction, chromatographic separation, and GC–MS analysis require more sample mass than will be available from samples returned to Earth from Mars. With its small sample mass requirement, Surface Enhanced Raman Spectroscopy could be an appropriate technique for analysis of returned samples. We have developed a SERS method for the detection of maleimide (2,5-pyrroledione), an N-containing heterocycle with a structure that is widespread in biochemicals. This semi-quantitative methodology accurately determines maleimide concentration in the range from 60 µg/mL to 120 µg/mL. We present a maleimide SERS standard spectrum which will be useful as a reference for future works. The present work demonstrates an easy, accurate, and effective method for the non-destructive qualitative and semi-quantitative study of maleimide as a first step toward developing a method for analysis of related compounds. |
| first_indexed | 2024-03-12T19:49:46Z |
| format | Article |
| id | doaj.art-1df1cdf8ed834956bf6d5333002f3a49 |
| institution | Directory Open Access Journal |
| issn | 1674-9871 |
| language | English |
| last_indexed | 2024-03-12T19:49:46Z |
| publishDate | 2021-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Geoscience Frontiers |
| spelling | doaj.art-1df1cdf8ed834956bf6d5333002f3a492023-08-02T03:14:22ZengElsevierGeoscience Frontiers1674-98712021-09-01125101226A new semi-quantitative Surface-Enhanced Raman Spectroscopy (SERS) method for detection of maleimide (2,5-pyrroledione) with potential application to astrobiologyJ. Aramendia0L. Gomez-Nubla1M.L. Tuite2K.H. Williford3K. Castro4J.M. Madariaga5Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Dr, Pasadena, CA 91109, United States; Department of Analytical Chemistry, University of the Basque Country UPV/EHU, P.O. Box 644, 48080 Bilbao, Spain; Corresponding author at: Department of Analytical Chemistry, University of the Basque Country UPV/EHU, P.O. Box 644, 48080 Bilbao, Spain.Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Dr, Pasadena, CA 91109, United StatesJet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Dr, Pasadena, CA 91109, United StatesJet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Dr, Pasadena, CA 91109, United StatesDepartment of Analytical Chemistry, University of the Basque Country UPV/EHU, P.O. Box 644, 48080 Bilbao, SpainDepartment of Analytical Chemistry, University of the Basque Country UPV/EHU, P.O. Box 644, 48080 Bilbao, SpainNitrogen-containing heterocyclic compounds are fundamental biochemical components of all life on Earth and, presumably, life elsewhere in our solar system. Detection and characterization of these compounds by traditional solvent extraction, chromatographic separation, and GC–MS analysis require more sample mass than will be available from samples returned to Earth from Mars. With its small sample mass requirement, Surface Enhanced Raman Spectroscopy could be an appropriate technique for analysis of returned samples. We have developed a SERS method for the detection of maleimide (2,5-pyrroledione), an N-containing heterocycle with a structure that is widespread in biochemicals. This semi-quantitative methodology accurately determines maleimide concentration in the range from 60 µg/mL to 120 µg/mL. We present a maleimide SERS standard spectrum which will be useful as a reference for future works. The present work demonstrates an easy, accurate, and effective method for the non-destructive qualitative and semi-quantitative study of maleimide as a first step toward developing a method for analysis of related compounds.http://www.sciencedirect.com/science/article/pii/S1674987121000906MaleimideSurface-Enhanced Raman SpectroscopyAstrobiologyBiosignatureExtraterrestrial life |
| spellingShingle | J. Aramendia L. Gomez-Nubla M.L. Tuite K.H. Williford K. Castro J.M. Madariaga A new semi-quantitative Surface-Enhanced Raman Spectroscopy (SERS) method for detection of maleimide (2,5-pyrroledione) with potential application to astrobiology Geoscience Frontiers Maleimide Surface-Enhanced Raman Spectroscopy Astrobiology Biosignature Extraterrestrial life |
| title | A new semi-quantitative Surface-Enhanced Raman Spectroscopy (SERS) method for detection of maleimide (2,5-pyrroledione) with potential application to astrobiology |
| title_full | A new semi-quantitative Surface-Enhanced Raman Spectroscopy (SERS) method for detection of maleimide (2,5-pyrroledione) with potential application to astrobiology |
| title_fullStr | A new semi-quantitative Surface-Enhanced Raman Spectroscopy (SERS) method for detection of maleimide (2,5-pyrroledione) with potential application to astrobiology |
| title_full_unstemmed | A new semi-quantitative Surface-Enhanced Raman Spectroscopy (SERS) method for detection of maleimide (2,5-pyrroledione) with potential application to astrobiology |
| title_short | A new semi-quantitative Surface-Enhanced Raman Spectroscopy (SERS) method for detection of maleimide (2,5-pyrroledione) with potential application to astrobiology |
| title_sort | new semi quantitative surface enhanced raman spectroscopy sers method for detection of maleimide 2 5 pyrroledione with potential application to astrobiology |
| topic | Maleimide Surface-Enhanced Raman Spectroscopy Astrobiology Biosignature Extraterrestrial life |
| url | http://www.sciencedirect.com/science/article/pii/S1674987121000906 |
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