Plasma Extracellular Vesicle Characteristics Correlate with Tumor Differentiation and Predict Overall Survival in Patients with Pancreatic Ductal Adenocarcinoma Undergoing Surgery with Curative Intent

Plasma Extracellular Vesicle Characteristics Correlate with Tumor Differentiation and Predict Overall Survival in Patients with Pancreatic Ductal Adenocarcinoma Undergoing Surgery with Curative Intent

Better preoperative characterization of patients with pancreatic ductal adenocarcinoma (PDAC) would aid in treatment optimization. Extracellular vesicles (EV) are promising, largely unexplored biomarkers in PDAC. This study aimed to evaluate if plasma EV characteristics are associated with PDAC clin...

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Bibliographic Details
Main Authors: David Badovinac, Katja Goričar, Hana Zavrtanik, Miha Petrič, Teja Lavrin, Nina Mavec, Vita Dolžan, Aleš Tomažič, Metka Lenassi
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Journal of Personalized Medicine
Subjects:
pancreatic cancer
extracellular vesicles
nanoparticle-tracking analysis
tumor differentiation
overall survival
plasma biomarkers
Online Access:https://www.mdpi.com/2075-4426/11/2/77

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