The Multifaceted Role of Confocal Laser Endomicroscopy in Head and Neck Surgery: Oncologic and Functional Insights
(1) Background: Confocal laser endomicroscopy (CLE) has emerged as a transformative tool in head and neck surgery, with applications spanning oncologic insights and functional evaluations. This study delves into CLE’s potential in these domains. (2) Methods: We performed CLE in head and neck oncolog...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-09-01
|
| Series: | Diagnostics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2075-4418/13/19/3081 |
| _version_ | 1797576006382387200 |
|---|---|
| author | Nina Wenda Kai Fruth Annette Fisseler-Eckhoff Jan Gosepath |
| author_facet | Nina Wenda Kai Fruth Annette Fisseler-Eckhoff Jan Gosepath |
| author_sort | Nina Wenda |
| collection | DOAJ |
| description | (1) Background: Confocal laser endomicroscopy (CLE) has emerged as a transformative tool in head and neck surgery, with applications spanning oncologic insights and functional evaluations. This study delves into CLE’s potential in these domains. (2) Methods: We performed CLE in head and neck oncologic surgery, focusing on tumor margin identification and precise resection. We also employed CLE for functional assessment in allergic rhinitis, observing real-time mucosal changes during nasal provocation testing. (3) Results: In oncologic surgery, CLE enabled real-time visualization of tumor margins and cellular patterns, aiding resection decisions. In allergic rhinitis assessment, CLE captured dynamic morphological alterations upon allergen exposure, enhancing understanding of mucosal reactions. (4) Conclusions: The integration of CLE with evolving technologies such as deep learning and AI holds promise for enhanced diagnostic accuracy. This study underscores CLE’s expansive potential, highlighting its role in guiding surgical choices and illuminating inflammatory processes in the head and neck. |
| first_indexed | 2024-03-10T21:46:22Z |
| format | Article |
| id | doaj.art-1e033393ef6a4c059a691ec2ede7a571 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T21:46:22Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-1e033393ef6a4c059a691ec2ede7a5712023-11-19T14:14:29ZengMDPI AGDiagnostics2075-44182023-09-011319308110.3390/diagnostics13193081The Multifaceted Role of Confocal Laser Endomicroscopy in Head and Neck Surgery: Oncologic and Functional InsightsNina Wenda0Kai Fruth1Annette Fisseler-Eckhoff2Jan Gosepath3Department of Otolaryngology, Head and Neck Surgery, Helios HSK Wiesbaden, 65199 Wiesbaden, GermanyDepartment of Otolaryngology, Head and Neck Surgery, Helios HSK Wiesbaden, 65199 Wiesbaden, GermanyDepartment of Pathology, Helios HSK Wiesbaden, 65199 Wiesbaden, GermanyDepartment of Otolaryngology, Head and Neck Surgery, Helios HSK Wiesbaden, 65199 Wiesbaden, Germany(1) Background: Confocal laser endomicroscopy (CLE) has emerged as a transformative tool in head and neck surgery, with applications spanning oncologic insights and functional evaluations. This study delves into CLE’s potential in these domains. (2) Methods: We performed CLE in head and neck oncologic surgery, focusing on tumor margin identification and precise resection. We also employed CLE for functional assessment in allergic rhinitis, observing real-time mucosal changes during nasal provocation testing. (3) Results: In oncologic surgery, CLE enabled real-time visualization of tumor margins and cellular patterns, aiding resection decisions. In allergic rhinitis assessment, CLE captured dynamic morphological alterations upon allergen exposure, enhancing understanding of mucosal reactions. (4) Conclusions: The integration of CLE with evolving technologies such as deep learning and AI holds promise for enhanced diagnostic accuracy. This study underscores CLE’s expansive potential, highlighting its role in guiding surgical choices and illuminating inflammatory processes in the head and neck.https://www.mdpi.com/2075-4418/13/19/3081real time imaging in head and neck surgeryCLEallergic rhinitisnasal provocation testing |
| spellingShingle | Nina Wenda Kai Fruth Annette Fisseler-Eckhoff Jan Gosepath The Multifaceted Role of Confocal Laser Endomicroscopy in Head and Neck Surgery: Oncologic and Functional Insights Diagnostics real time imaging in head and neck surgery CLE allergic rhinitis nasal provocation testing |
| title | The Multifaceted Role of Confocal Laser Endomicroscopy in Head and Neck Surgery: Oncologic and Functional Insights |
| title_full | The Multifaceted Role of Confocal Laser Endomicroscopy in Head and Neck Surgery: Oncologic and Functional Insights |
| title_fullStr | The Multifaceted Role of Confocal Laser Endomicroscopy in Head and Neck Surgery: Oncologic and Functional Insights |
| title_full_unstemmed | The Multifaceted Role of Confocal Laser Endomicroscopy in Head and Neck Surgery: Oncologic and Functional Insights |
| title_short | The Multifaceted Role of Confocal Laser Endomicroscopy in Head and Neck Surgery: Oncologic and Functional Insights |
| title_sort | multifaceted role of confocal laser endomicroscopy in head and neck surgery oncologic and functional insights |
| topic | real time imaging in head and neck surgery CLE allergic rhinitis nasal provocation testing |
| url | https://www.mdpi.com/2075-4418/13/19/3081 |
| work_keys_str_mv | AT ninawenda themultifacetedroleofconfocallaserendomicroscopyinheadandnecksurgeryoncologicandfunctionalinsights AT kaifruth themultifacetedroleofconfocallaserendomicroscopyinheadandnecksurgeryoncologicandfunctionalinsights AT annettefisselereckhoff themultifacetedroleofconfocallaserendomicroscopyinheadandnecksurgeryoncologicandfunctionalinsights AT jangosepath themultifacetedroleofconfocallaserendomicroscopyinheadandnecksurgeryoncologicandfunctionalinsights AT ninawenda multifacetedroleofconfocallaserendomicroscopyinheadandnecksurgeryoncologicandfunctionalinsights AT kaifruth multifacetedroleofconfocallaserendomicroscopyinheadandnecksurgeryoncologicandfunctionalinsights AT annettefisselereckhoff multifacetedroleofconfocallaserendomicroscopyinheadandnecksurgeryoncologicandfunctionalinsights AT jangosepath multifacetedroleofconfocallaserendomicroscopyinheadandnecksurgeryoncologicandfunctionalinsights |