Recurring RNA structural motifs underlie the mechanics of L1 stalk movement

Translocation of the tRNA on the ribosome is associated with large-scale molecular movements of the ribosomal L1 stalk. Here the authors identify the key determinants that allow these dramatic movements, and suggest they represent general strategies used to enable large-scale motions in functional R...

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Main Authors: Srividya Mohan, Harry F Noller
Format: Article
Language:English
Published: Nature Portfolio 2017-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms14285
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author Srividya Mohan
Harry F Noller
author_facet Srividya Mohan
Harry F Noller
author_sort Srividya Mohan
collection DOAJ
description Translocation of the tRNA on the ribosome is associated with large-scale molecular movements of the ribosomal L1 stalk. Here the authors identify the key determinants that allow these dramatic movements, and suggest they represent general strategies used to enable large-scale motions in functional RNAs.
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spelling doaj.art-1e051b97dfc94477a0e236c4b2dd57602022-12-21T18:32:11ZengNature PortfolioNature Communications2041-17232017-02-018111110.1038/ncomms14285Recurring RNA structural motifs underlie the mechanics of L1 stalk movementSrividya Mohan0Harry F Noller1Center for Molecular Biology of RNA and Department of Molecular, Cell and Developmental Biology, University of California at Santa CruzCenter for Molecular Biology of RNA and Department of Molecular, Cell and Developmental Biology, University of California at Santa CruzTranslocation of the tRNA on the ribosome is associated with large-scale molecular movements of the ribosomal L1 stalk. Here the authors identify the key determinants that allow these dramatic movements, and suggest they represent general strategies used to enable large-scale motions in functional RNAs.https://doi.org/10.1038/ncomms14285
spellingShingle Srividya Mohan
Harry F Noller
Recurring RNA structural motifs underlie the mechanics of L1 stalk movement
Nature Communications
title Recurring RNA structural motifs underlie the mechanics of L1 stalk movement
title_full Recurring RNA structural motifs underlie the mechanics of L1 stalk movement
title_fullStr Recurring RNA structural motifs underlie the mechanics of L1 stalk movement
title_full_unstemmed Recurring RNA structural motifs underlie the mechanics of L1 stalk movement
title_short Recurring RNA structural motifs underlie the mechanics of L1 stalk movement
title_sort recurring rna structural motifs underlie the mechanics of l1 stalk movement
url https://doi.org/10.1038/ncomms14285
work_keys_str_mv AT srividyamohan recurringrnastructuralmotifsunderliethemechanicsofl1stalkmovement
AT harryfnoller recurringrnastructuralmotifsunderliethemechanicsofl1stalkmovement