The protection of CoronaVac against the infection of wild‐type SARS‐CoV‐2 (WH‐09) or Omicron variant in nude‐hACE2 mice
Abstract Background Immunocompromised individuals have an increased risk of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection and severe outcomes, but we pay less attention to these people. Athymic nude mice are a murine strain with a spontaneous deficiency of the Foxn1 gene, wh...
Main Authors: | Kaili Lin, Meixuan Liu, Lu Sun, Hanjun Fu, Hongwei Qiao, Shunyi Wang, Sidan Pan, Hong Gao |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2023-08-01
|
Series: | Animal Models and Experimental Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1002/ame2.12336 |
Similar Items
-
Computational design of medicinal compounds to inhibit RBD-hACE2 interaction in the Omicron variant: unveiling a vulnerable target site
by: Muhammad Shahab, et al.
Published: (2023-01-01) -
Comparison of the pathogenesis of SARS-CoV-2 infection in K18-hACE2 mouse and Syrian golden hamster models
by: Haengdueng Jeong, et al.
Published: (2022-11-01) -
Effect of severe acute respiratory syndrome coronavirus 2 infection during pregnancy in K18-hACE2 transgenic mice
by: Byeongseok Kim, et al.
Published: (2023-01-01) -
SARS-CoV-2 omicron BA.5 and XBB variants have increased neurotropic potential over BA.1 in K18-hACE2 mice and human brain organoids
by: Romal Stewart, et al.
Published: (2023-11-01) -
Molecular Docking and Dynamics Simulation Revealed the Potential Inhibitory Activity of ACEIs Against SARS-CoV-2 Targeting the hACE2 Receptor
by: Ahmed A. Al-Karmalawy, et al.
Published: (2021-05-01)