Case report: acute liver failure induced by paracetamol toxicity

Case report: acute liver failure induced by paracetamol toxicity

Introduction. Paracetamol is the most commonly used drug across Western Europe and North America. There is no such trend of using Paracetamol in the Republic of Moldova, thus overdose cases are extremely rare. The mechanisms leading to overdose episodes might induce hepatotoxicity. Clinical case. T...

Bibliografski detalji
Glavni autori:	Eugen TCACIUC, Mariana PODUREAN, Olga SCHIOPU, Aurel BATRINAC, Angela SELIVANOV, Dumitru COLOMAN
Format:	Članak
Jezik:	English
Izdano:	Asociatia de Biosiguranta si Biosecuritate 2021-01-01
Serija:	One Health & Risk Management
Teme:	paracetamol overdose n-acetyl-cysteine hepatotoxicity acute liver failure
Online pristup:	https://journal.ohrm.bba.md/index.php/journal-ohrm-bba-md/article/view/88/66

Slični predmeti

Co-administration of fresh grape fruit juice (GFJ) and bergamottin prevented paracetamol induced hepatotoxicity after paracetamol overdose in rats
od: Refuoe Baleni, i dr.
Izdano: (2015-01-01)

Unintentional overdose of paracetamol as a problem of modern times - a case report
od: Kinga Pożarowska, i dr.
Izdano: (2022-08-01)

Risk Factors for Hepatotoxicity Due to Paracetamol Overdose in Adults
od: Iwona Popiolek, i dr.
Izdano: (2021-07-01)

Hepatoprotective effects of BPC-157 - paracetamol overdose
od: Sara Burić, i dr.
Izdano: (2023-01-01)

Paracetamol overdose: Analysis of a sample from a tertiary hospital in Eastern Saudi Arabia
od: Mohammed A Almansori, i dr.
Izdano: (2015-01-01)

Evaluation of cut-off values in acute paracetamol overdose following the United Kingdom guidelines
od: Hyun Ho Jeong, i dr.
Izdano: (2022-01-01)

Chlorzoxazone reduced the paracetamol-induced toxicity via competitive inhibition of CYP2E1-mediated metabolism
od: Ravindra Babu Pingili, i dr.
Izdano: (2023-04-01)

Effect of Different Doses of Paracetamol on Liver Enzyme Activities in White Albino Male Mice
od: Arieg A.W. Mohammad
Izdano: (2013-05-01)

Hepatoprotective potential of Convolvulus arvensis against paracetamol-induced hepatotoxicity
od: Mohsin Ali, i dr.
Izdano: (2013-07-01)

Paracetamol self-poisoning: when oral N-acetylcysteine saves life? a case report
od: Said Benlamkaddem, i dr.
Izdano: (2018-01-01)

Protection efficiency of red radish seeds and roots against paracetamol mediated hepatotoxicity in rats
od: Doha A. Mohamed, i dr.
Izdano: (2019-10-01)

Paracetamol overdose associated with cortical blindness-complicated acute leukoencephalopathy: a case report
od: Ruba Khasawneh, i dr.
Izdano: (2024-11-01)

Potential deleterious effects of paracetamol dose regime used in Nigeria versus that of the United States of America
od: Samuel James Offor, i dr.
Izdano: (2022-01-01)

Effect of n-hexane extract of Tinospora crispa on reduced glutathione and malondialdehyde level in paracetamol induced hepatotoxicity in rats
od: Emon Rashid, i dr.
Izdano: (2018-12-01)

Paracetamol misusing to dental pain: a case-report and recommandations for treatment
od: Debortoli Cyril, i dr.
Izdano: (2021-01-01)

Delayed presentation of paracetamol overdose
od: Johnre Retief Els, i dr.
Izdano: (2020-09-01)

Analysis of artocarpin content and hepatoprotective activity of ethanol extract of mobe (Artocarpus lacucha Buch-Ham.) leaves on the liver of rats induced by paracetamol
od: Efrata Citra Manta Surbakti, i dr.
Izdano: (2025-05-01)

The management and clinical outcome of paracetamol poisoning in South African adults: A single-centre retrospective review
od: C Kotze, i dr.
Izdano: (2024-11-01)

N-Acetylcysteine for Preventing Acetaminophen-Induced Liver Injury: A Comprehensive Review
od: Anna Licata, i dr.
Izdano: (2022-08-01)

Modulation of Paracetamol-Induced Hepatotoxicity by Acute and Chronic Ethanol Consumption in Mice: A Study Pilot
od: Allan Cristian Gonçalves, i dr.
Izdano: (2024-11-01)

Paracetamol overdosing with 6500 mg single dose: Case report
od: Murthy Shiva N., i dr.
Izdano: (2022-01-01)

Glucosamine-paracetamol spray-dried solid dispersions with maximized intrinsic dissolution rate, bioavailability and decreased levels of in vivo toxic metabolites
od: Ali AMA, i dr.
Izdano: (2018-09-01)

Changes in haematological and biochemical blood parameters of C57Bl/6 mice in acute paracetamol poisoning
od: A. I. Zudova, i dr.
Izdano: (2025-02-01)

The Hepatoprotective Effect of Omega-7 Against Paracetamol-Induced Hepatotoxicity in Male Rats
od: Hadeel Ali Hameed, i dr.
Izdano: (2023-12-01)

Antioxidant, hepatoprotective & nephroprotective potential of a novel synthetic compound 2′, 3′-dihydroxybenzylidene in paracetamol intoxicated rats
od: Mohammad Attaullah, i dr.
Izdano: (2023-12-01)

Medicinal plants in the protection and treatment of liver diseases
od: Mohammad Saleem, i dr.
Izdano: (2014-10-01)

Paracetamol overdose causing acute kidney injury without hepatotoxicity: a case report
od: Micha Saad, i dr.
Izdano: (2024-07-01)

Effects of Enzyme Induction and/or Glutathione Depletion on Methimazole Induced Hepatotoxicity in Mice and the Protective Role of N-Acetylcysteine
od: Reza Heidari, i dr.
Izdano: (2014-03-01)

Effects of N-acetyl cysteine, vitamin E and vitamin C on liver glutathione levels following amiodarone treatment in rats
od: Esin Akbay, i dr.
Izdano: (2019-06-01)

Hepatoprotective potential of ethanolic extract of Aquilaria agallocha leaves against paracetamol induced hepatotoxicity in SD rats
od: Janey Alam, i dr.
Izdano: (2017-01-01)

Preventive treatment with guarana powder (Paullinia cupana) mitigates acute paracetamol-induced hepatotoxicity by modulating oxidative stress
od: Clécia Dias Teixeira, i dr.
Izdano: (2025-06-01)

Comparison of effects of high and low dose paracetamol treatment and toxicity on brain and liver in rats
od: Ersoy Oksuz, i dr.
Izdano: (2020-12-01)

Fisetin Attenuates Paracetamol-Induced Hepatotoxicity by Regulating CYP2E1 Enzyme
od: RUSTEM A. UGAN, i dr.
Izdano: (2023-04-01)

Editorial: Multiscale modeling for the liver
od: Harvey Ho, i dr.
Izdano: (2023-04-01)

N-Acetyl Cysteine Overdose Inducing Hepatic Steatosis and Systemic Inflammation in Both Propacetamol-Induced Hepatotoxic and Normal Mice
od: Gunn-Guang Liou, i dr.
Izdano: (2021-03-01)

Management of acetaminophen toxicity, a review
od: Alejandra Beltrán-Olazábal, i dr.
Izdano: (2019-10-01)

The Antioxidant and Hepatoprotective Potential of Berberine and Silymarin on Acetaminophen Induced Toxicity in <i>Cyprinus carpio</i> L.
od: Lăcrămioara Grădinariu, i dr.
Izdano: (2024-01-01)

Protective Effects of Berberis Vulgaris Plant Extract on Paracetamol-induced Liver Toxicity in Rats
od: Serdar Yiğit, i dr.
Izdano: (2022-10-01)

Risk factors for the need for advanced care among prescription and over‐the‐counter drug overdose patients
od: Chie Tanaka, i dr.
Izdano: (2024-01-01)

Two chromatographic methods for analyzing paracetamol in spiked human plasma with its toxic metabolite, N-acetyl parabenzoquinone imine and its antidote, N-acetyl-l-cysteine
od: Omar M El-Abassy, i dr.
Izdano: (2025-02-01)