A short appraisal of nanodiamonds in drug delivery and targeting: recent advancements

Nanodiamonds have emerged as a powerful tool in the field of drug delivery, offering exciting recent advancements and promising future prospects. Recent research has focused on enhancing drug loading efficiency, targeted delivery, and precision medicine using nanodiamonds. Strategies such as surface...

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Main Authors: Dilpreet Singh, Supriya Ray
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Nanotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnano.2023.1259648/full
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author Dilpreet Singh
Supriya Ray
author_facet Dilpreet Singh
Supriya Ray
author_sort Dilpreet Singh
collection DOAJ
description Nanodiamonds have emerged as a powerful tool in the field of drug delivery, offering exciting recent advancements and promising future prospects. Recent research has focused on enhancing drug loading efficiency, targeted delivery, and precision medicine using nanodiamonds. Strategies such as surface functionalization, polymer coatings, and encapsulation techniques have been optimized to improve drug loading, stability, and controlled release. Nanodiamonds have shown potential in targeted drug delivery through the incorporation of targeting ligands, enabling site-specific drug delivery and improved therapeutic outcomes. Additionally, nanodiamonds allow for combination therapy by carrying multiple drugs simultaneously, opening avenues for synergistic treatments. Stimuli-responsive nanodiamonds have been developed for precise and controlled drug release. Overcoming biological barriers, such as the blood-brain barrier, has been investigated by modifying nanodiamonds’ surfaces. Recent studies have highlighted innovative strategies for loading a variety of therapeutic cargoes onto nanodiamond platforms, including small molecules, proteins, nucleic acids, and even gene-editing tools. Future prospects include the integration of nanodiamonds with emerging technologies and addressing biocompatibility and safety concerns. Despite the need for further research and clinical studies, the recent advancements and future prospects of nanodiamonds in drug delivery suggest their potential to revolutionize the field and enhance patient care.
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spelling doaj.art-1e16203da4844707895f53b5762f07272023-08-31T06:47:49ZengFrontiers Media S.A.Frontiers in Nanotechnology2673-30132023-08-01510.3389/fnano.2023.12596481259648A short appraisal of nanodiamonds in drug delivery and targeting: recent advancementsDilpreet SinghSupriya RayNanodiamonds have emerged as a powerful tool in the field of drug delivery, offering exciting recent advancements and promising future prospects. Recent research has focused on enhancing drug loading efficiency, targeted delivery, and precision medicine using nanodiamonds. Strategies such as surface functionalization, polymer coatings, and encapsulation techniques have been optimized to improve drug loading, stability, and controlled release. Nanodiamonds have shown potential in targeted drug delivery through the incorporation of targeting ligands, enabling site-specific drug delivery and improved therapeutic outcomes. Additionally, nanodiamonds allow for combination therapy by carrying multiple drugs simultaneously, opening avenues for synergistic treatments. Stimuli-responsive nanodiamonds have been developed for precise and controlled drug release. Overcoming biological barriers, such as the blood-brain barrier, has been investigated by modifying nanodiamonds’ surfaces. Recent studies have highlighted innovative strategies for loading a variety of therapeutic cargoes onto nanodiamond platforms, including small molecules, proteins, nucleic acids, and even gene-editing tools. Future prospects include the integration of nanodiamonds with emerging technologies and addressing biocompatibility and safety concerns. Despite the need for further research and clinical studies, the recent advancements and future prospects of nanodiamonds in drug delivery suggest their potential to revolutionize the field and enhance patient care.https://www.frontiersin.org/articles/10.3389/fnano.2023.1259648/fullnanodiamondsstructural featuressurface modificationdrug targetingtranslational potential
spellingShingle Dilpreet Singh
Supriya Ray
A short appraisal of nanodiamonds in drug delivery and targeting: recent advancements
Frontiers in Nanotechnology
nanodiamonds
structural features
surface modification
drug targeting
translational potential
title A short appraisal of nanodiamonds in drug delivery and targeting: recent advancements
title_full A short appraisal of nanodiamonds in drug delivery and targeting: recent advancements
title_fullStr A short appraisal of nanodiamonds in drug delivery and targeting: recent advancements
title_full_unstemmed A short appraisal of nanodiamonds in drug delivery and targeting: recent advancements
title_short A short appraisal of nanodiamonds in drug delivery and targeting: recent advancements
title_sort short appraisal of nanodiamonds in drug delivery and targeting recent advancements
topic nanodiamonds
structural features
surface modification
drug targeting
translational potential
url https://www.frontiersin.org/articles/10.3389/fnano.2023.1259648/full
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