The Italian Unitary Society of Colon-proctology (SIUCP: Società Italiana Unitaria di Colonproctologia) guidelines for the management of anal fissure

Abstract Introduction The aim of these evidence-based guidelines is to present a consensus position from members of the Italian Unitary Society of Colon-Proctology (SIUCP: Società Italiana Unitaria di Colon-Proctologia) on the diagnosis and management of anal fissure, with the purpose to guide every...

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Main Authors: Antonio Brillantino, Adolfo Renzi, Pasquale Talento, Francesca Iacobellis, Luigi Brusciano, Luigi Monaco, Domenico Izzo, Alfredo Giordano, Michele Pinto, Corrado Fantini, Marcello Gasparrini, Michele Schiano Di Visconte, Francesca Milazzo, Giovanni Ferreri, Andrea Braini, Umberto Cocozza, Massimo Pezzatini, Valeria Gianfreda, Alberto Di Leo, Vincenzo Landolfi, Umberto Favetta, Sergio Agradi, Giovanni Marino, Massimilano Varriale, Massimo Mongardini, Claudio Eduardo Fernando Antonio Pagano, Riccardo Brachet Contul, Nando Gallese, Giampiero Ucchino, Michele D’Ambra, Roberto Rizzato, Giacomo Sarzo, Bruno Masci, Francesca Da Pozzo, Simona Ascanelli, Fabrizio Foroni, Alessio Palumbo, Patrizia Liguori, Angela Pezzolla, Luigi Marano, Antonio Capomagi, Eugenio Cudazzo, Francesca Babic, Carmelo Geremia, Alessandro Bussotti, Mario Cicconi, Antonia Di Sarno, Federico Maria Mongardini, Antonio Brescia, Leonardo Lenisa, Massimiliano Mistrangelo, Maria Laura Sandoval Sotelo, Luciano Vicenzo, Antonio Longo, Ludovico Docimo
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Surgery
Subjects:
Online Access:https://doi.org/10.1186/s12893-023-02223-z
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author Antonio Brillantino
Adolfo Renzi
Pasquale Talento
Francesca Iacobellis
Luigi Brusciano
Luigi Monaco
Domenico Izzo
Alfredo Giordano
Michele Pinto
Corrado Fantini
Marcello Gasparrini
Michele Schiano Di Visconte
Francesca Milazzo
Giovanni Ferreri
Andrea Braini
Umberto Cocozza
Massimo Pezzatini
Valeria Gianfreda
Alberto Di Leo
Vincenzo Landolfi
Umberto Favetta
Sergio Agradi
Giovanni Marino
Massimilano Varriale
Massimo Mongardini
Claudio Eduardo Fernando Antonio Pagano
Riccardo Brachet Contul
Nando Gallese
Giampiero Ucchino
Michele D’Ambra
Roberto Rizzato
Giacomo Sarzo
Bruno Masci
Francesca Da Pozzo
Simona Ascanelli
Fabrizio Foroni
Alessio Palumbo
Patrizia Liguori
Angela Pezzolla
Luigi Marano
Antonio Capomagi
Eugenio Cudazzo
Francesca Babic
Carmelo Geremia
Alessandro Bussotti
Mario Cicconi
Antonia Di Sarno
Federico Maria Mongardini
Antonio Brescia
Leonardo Lenisa
Massimiliano Mistrangelo
Maria Laura Sandoval Sotelo
Luciano Vicenzo
Antonio Longo
Ludovico Docimo
author_facet Antonio Brillantino
Adolfo Renzi
Pasquale Talento
Francesca Iacobellis
Luigi Brusciano
Luigi Monaco
Domenico Izzo
Alfredo Giordano
Michele Pinto
Corrado Fantini
Marcello Gasparrini
Michele Schiano Di Visconte
Francesca Milazzo
Giovanni Ferreri
Andrea Braini
Umberto Cocozza
Massimo Pezzatini
Valeria Gianfreda
Alberto Di Leo
Vincenzo Landolfi
Umberto Favetta
Sergio Agradi
Giovanni Marino
Massimilano Varriale
Massimo Mongardini
Claudio Eduardo Fernando Antonio Pagano
Riccardo Brachet Contul
Nando Gallese
Giampiero Ucchino
Michele D’Ambra
Roberto Rizzato
Giacomo Sarzo
Bruno Masci
Francesca Da Pozzo
Simona Ascanelli
Fabrizio Foroni
Alessio Palumbo
Patrizia Liguori
Angela Pezzolla
Luigi Marano
Antonio Capomagi
Eugenio Cudazzo
Francesca Babic
Carmelo Geremia
Alessandro Bussotti
Mario Cicconi
Antonia Di Sarno
Federico Maria Mongardini
Antonio Brescia
Leonardo Lenisa
Massimiliano Mistrangelo
Maria Laura Sandoval Sotelo
Luciano Vicenzo
Antonio Longo
Ludovico Docimo
author_sort Antonio Brillantino
collection DOAJ
description Abstract Introduction The aim of these evidence-based guidelines is to present a consensus position from members of the Italian Unitary Society of Colon-Proctology (SIUCP: Società Italiana Unitaria di Colon-Proctologia) on the diagnosis and management of anal fissure, with the purpose to guide every physician in the choice of the best treatment option, according with the available literature. Methods A panel of experts was designed and charged by the Board of the SIUCP to develop key-questions on the main topics covering the management of anal fissure and to performe an accurate search on each topic in different databanks, in order to provide evidence-based answers to the questions and to summarize them in statements. All the clinical questions were discussed by the expert panel in different rounds through the Delphi approach and, for each statement, a consensus among the experts was reached. The questions were created according to the PICO criteria, and the statements developed adopting the GRADE methodology. Conclusions In patients with acute anal fissure the medical therapy with dietary and behavioral norms is indicated. In the chronic phase of disease, the conservative treatment with topical 0.3% nifedipine plus 1.5% lidocaine or nitrates may represent the first-line therapy, eventually associated with ointments with film-forming, anti-inflammatory and healing properties such as Propionibacterium extract gel. In case of first-line treatment failure, the surgical strategy (internal sphincterotomy or fissurectomy with flap), may be guided by the clinical findings, eventually supported by endoanal ultrasound and anal manometry.
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spelling doaj.art-1e173aaaf91e4ae9a13315dc6f327e492023-11-26T12:11:31ZengBMCBMC Surgery1471-24822023-10-0123111910.1186/s12893-023-02223-zThe Italian Unitary Society of Colon-proctology (SIUCP: Società Italiana Unitaria di Colonproctologia) guidelines for the management of anal fissureAntonio Brillantino0Adolfo Renzi1Pasquale Talento2Francesca Iacobellis3Luigi Brusciano4Luigi Monaco5Domenico Izzo6Alfredo Giordano7Michele Pinto8Corrado Fantini9Marcello Gasparrini10Michele Schiano Di Visconte11Francesca Milazzo12Giovanni Ferreri13Andrea Braini14Umberto Cocozza15Massimo Pezzatini16Valeria Gianfreda17Alberto Di Leo18Vincenzo Landolfi19Umberto Favetta20Sergio Agradi21Giovanni Marino22Massimilano Varriale23Massimo Mongardini24Claudio Eduardo Fernando Antonio Pagano25Riccardo Brachet Contul26Nando Gallese27Giampiero Ucchino28Michele D’Ambra29Roberto Rizzato30Giacomo Sarzo31Bruno Masci32Francesca Da Pozzo33Simona Ascanelli34Fabrizio Foroni35Alessio Palumbo36Patrizia Liguori37Angela Pezzolla38Luigi Marano39Antonio Capomagi40Eugenio Cudazzo41Francesca Babic42Carmelo Geremia43Alessandro Bussotti44Mario Cicconi45Antonia Di Sarno46Federico Maria Mongardini47Antonio Brescia48Leonardo Lenisa49Massimiliano Mistrangelo50Maria Laura Sandoval Sotelo51Luciano Vicenzo52Antonio Longo53Ludovico Docimo54Deparment of Surgery, “A. Cardarelli” Hospital“Buonconsiglio-Fatebenefratelli” HospitalDepartment of Surgery, Pelvic Floor Center, AUSL-IRCCS Reggio EmiliaDepartment of General and Emergency Radiology, “A. Cardarelli” HospitalDepartment of Advanced Medical and Surgical Sciences, University of Campania “L. Vanvitelli”“Pineta Grande” Hospital, “Villa Esther” ClinicDepartment of General and Emergency Surgery, AORN dei Colli Monaldi-Cotugno-CTO, CTO HospitalDepartment of General and Emergency Surgery, University of Salerno, Hospital of Mercato San SeverinoHumanitas CastelliDepartment of Surgery, “Dei Pellegrini” Hospital, ASL Napoli 1Oncologic Colorectal Unit, “Sant’Andrea” University HospitalDepartment of General Surgery, Colorectal and Pelvic Floor Diseases Center, “Santa Maria Dei Battuti” HospitalDepartment of Surgery, Pelvic Floor Center, AUSL-IRCCS Reggio EmiliaDepartment of Surgery, Pelvic Floor Center, AUSL-IRCCS Reggio EmiliaDepartment of General Surgery, Azienda Sanitaria Friuli Occidentale (ASFO)Department of General Surgery, “S. Maria Degli Angeli” Hospital“Dei Castelli” Hospital, ASL Roma 6Unit of Colonproctologic and Pelvic Surgery, “M.G. Vannini” HospitalDepartment of General and Minivasive Surgery, “San Camillo” HospitalDepartment of General and Specalist Surgery, AORN “S.G. Moscati”Unit of Proctology and Pelvic Surgery, “Città di Pavia” ClinicHumanitas Gavazzeni/Castelli BergamoDepartment of General Surgery, “Santa Marta e Santa Venera” Hospital of AcirealeDepartment of General and Emergency Surgery, “Sandro Pertini” Hospital, Asl Roma 2“La Sapienza” University of Rome, “Umberto1” PolyclinicUnit of Proctology and Pelvic Surgery, “Città di Pavia” ClinicGeneral Ad Urgent Surgery, “U. Parini” Regional HospitalUnit of Proctologic Surgery, “Sant’Antonio” ClinicUnit of General Surgery, “Maggiore” HospitalDepartment of General and Oncologic-Minivasive Surgery, “Federico II” UniversityDepartment of General Surgery, Hospital of Conegliano AULSS 2Department of General Surgery, University of Padova, “Sant’Antonio” Hospital“San Carlo di Nancy” HospitalDepartment of Surgery, “Santa Maria dei battuti” Hospital, San Vito al TagliamentoDepartment of Surgery, University Hospital of FerraraDeparment of Surgery, “A. Cardarelli” HospitalDeparment of Surgery, “A. Cardarelli” HospitalDepartment of Surgery, “Mater Dei” HospitalDepartment of Surgery, University Aldo MoroAcademy of Applied Medical and Social Sciences - AMiSNS: Akademia Medycznych i Spolecznych Nauk Stosowanych“Montanari” Hospital, Morciano di RomagnaDepartment of Surgery, Pelvic Floor Center, AUSL-IRCCS Reggio EmiliaDepartment of Surgery, Hospital of Cattinara, ASUGI TriesteUnit of Proctology and Pelvic Surgery, “Città di Pavia” Clinic“San Carlo Di Nancy” HospitalDepartment of General Surgery, “Sant’Omero-Val Vibrata” Hospital“Buonconsiglio-Fatebenefratelli” HospitalDepartment of Advanced Medical and Surgical Sciences, University of Campania “L. Vanvitelli”Department of Oncologic Colorectal Surgery, University Hospital S. Andrea, “La Sapienza” UniversityDepartment of Surgery, Humanitas San Pio X, Surgery Unit, Pelvic Floor CentreDepartment of Surgery, “Le Molinette” HospitalDeparment of Surgery, “A. Cardarelli” HospitalDeparment of Surgery, “A. Cardarelli” Hospital“Madonna Della Fiducia” ClinicDepartment of Advanced Medical and Surgical Sciences, University of Campania “L. Vanvitelli”Abstract Introduction The aim of these evidence-based guidelines is to present a consensus position from members of the Italian Unitary Society of Colon-Proctology (SIUCP: Società Italiana Unitaria di Colon-Proctologia) on the diagnosis and management of anal fissure, with the purpose to guide every physician in the choice of the best treatment option, according with the available literature. Methods A panel of experts was designed and charged by the Board of the SIUCP to develop key-questions on the main topics covering the management of anal fissure and to performe an accurate search on each topic in different databanks, in order to provide evidence-based answers to the questions and to summarize them in statements. All the clinical questions were discussed by the expert panel in different rounds through the Delphi approach and, for each statement, a consensus among the experts was reached. The questions were created according to the PICO criteria, and the statements developed adopting the GRADE methodology. Conclusions In patients with acute anal fissure the medical therapy with dietary and behavioral norms is indicated. In the chronic phase of disease, the conservative treatment with topical 0.3% nifedipine plus 1.5% lidocaine or nitrates may represent the first-line therapy, eventually associated with ointments with film-forming, anti-inflammatory and healing properties such as Propionibacterium extract gel. In case of first-line treatment failure, the surgical strategy (internal sphincterotomy or fissurectomy with flap), may be guided by the clinical findings, eventually supported by endoanal ultrasound and anal manometry.https://doi.org/10.1186/s12893-023-02223-zAnal fissureAnal spasmEndoanal ultrasoundAnal manometryAnal dilatationSphincterotomy
spellingShingle Antonio Brillantino
Adolfo Renzi
Pasquale Talento
Francesca Iacobellis
Luigi Brusciano
Luigi Monaco
Domenico Izzo
Alfredo Giordano
Michele Pinto
Corrado Fantini
Marcello Gasparrini
Michele Schiano Di Visconte
Francesca Milazzo
Giovanni Ferreri
Andrea Braini
Umberto Cocozza
Massimo Pezzatini
Valeria Gianfreda
Alberto Di Leo
Vincenzo Landolfi
Umberto Favetta
Sergio Agradi
Giovanni Marino
Massimilano Varriale
Massimo Mongardini
Claudio Eduardo Fernando Antonio Pagano
Riccardo Brachet Contul
Nando Gallese
Giampiero Ucchino
Michele D’Ambra
Roberto Rizzato
Giacomo Sarzo
Bruno Masci
Francesca Da Pozzo
Simona Ascanelli
Fabrizio Foroni
Alessio Palumbo
Patrizia Liguori
Angela Pezzolla
Luigi Marano
Antonio Capomagi
Eugenio Cudazzo
Francesca Babic
Carmelo Geremia
Alessandro Bussotti
Mario Cicconi
Antonia Di Sarno
Federico Maria Mongardini
Antonio Brescia
Leonardo Lenisa
Massimiliano Mistrangelo
Maria Laura Sandoval Sotelo
Luciano Vicenzo
Antonio Longo
Ludovico Docimo
The Italian Unitary Society of Colon-proctology (SIUCP: Società Italiana Unitaria di Colonproctologia) guidelines for the management of anal fissure
BMC Surgery
Anal fissure
Anal spasm
Endoanal ultrasound
Anal manometry
Anal dilatation
Sphincterotomy
title The Italian Unitary Society of Colon-proctology (SIUCP: Società Italiana Unitaria di Colonproctologia) guidelines for the management of anal fissure
title_full The Italian Unitary Society of Colon-proctology (SIUCP: Società Italiana Unitaria di Colonproctologia) guidelines for the management of anal fissure
title_fullStr The Italian Unitary Society of Colon-proctology (SIUCP: Società Italiana Unitaria di Colonproctologia) guidelines for the management of anal fissure
title_full_unstemmed The Italian Unitary Society of Colon-proctology (SIUCP: Società Italiana Unitaria di Colonproctologia) guidelines for the management of anal fissure
title_short The Italian Unitary Society of Colon-proctology (SIUCP: Società Italiana Unitaria di Colonproctologia) guidelines for the management of anal fissure
title_sort italian unitary society of colon proctology siucp societa italiana unitaria di colonproctologia guidelines for the management of anal fissure
topic Anal fissure
Anal spasm
Endoanal ultrasound
Anal manometry
Anal dilatation
Sphincterotomy
url https://doi.org/10.1186/s12893-023-02223-z
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AT massimilanovarriale italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT massimomongardini italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT claudioeduardofernandoantoniopagano italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT riccardobrachetcontul italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT nandogallese italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT giampieroucchino italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT micheledambra italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT robertorizzato italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT giacomosarzo italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT brunomasci italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT francescadapozzo italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT simonaascanelli italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT fabrizioforoni italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT alessiopalumbo italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT patrizialiguori italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT angelapezzolla italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT luigimarano italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT antoniocapomagi italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT eugeniocudazzo italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT francescababic italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT carmelogeremia italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT alessandrobussotti italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT mariocicconi italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT antoniadisarno italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT federicomariamongardini italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT antoniobrescia italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT leonardolenisa italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT massimilianomistrangelo italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT marialaurasandovalsotelo italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT lucianovicenzo italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT antoniolongo italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure
AT ludovicodocimo italianunitarysocietyofcolonproctologysiucpsocietaitalianaunitariadicolonproctologiaguidelinesforthemanagementofanalfissure