Autistic and Catatonic Spectrum Symptoms in Patients with Borderline Personality Disorder
Background: Recent literature has shown that a considerable percentage of patients with severe mental disorders can develop, over time, full-blown or subthreshold catatonia. Some studies corroborate the model of an illness trajectory in which different mental disorders would be arranged along a cont...
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| Format: | Article |
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MDPI AG
2023-08-01
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| Series: | Brain Sciences |
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| Online Access: | https://www.mdpi.com/2076-3425/13/8/1175 |
| _version_ | 1797585295345975296 |
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| author | Liliana Dell’Osso Giulia Amatori Ivan Mirko Cremone Enrico Massimetti Benedetta Nardi Davide Gravina Francesca Benedetti Maria Rosaria Anna Muscatello Maurizio Pompili Pierluigi Politi Antonio Vita Mario Maj Barbara Carpita |
| author_facet | Liliana Dell’Osso Giulia Amatori Ivan Mirko Cremone Enrico Massimetti Benedetta Nardi Davide Gravina Francesca Benedetti Maria Rosaria Anna Muscatello Maurizio Pompili Pierluigi Politi Antonio Vita Mario Maj Barbara Carpita |
| author_sort | Liliana Dell’Osso |
| collection | DOAJ |
| description | Background: Recent literature has shown that a considerable percentage of patients with severe mental disorders can develop, over time, full-blown or subthreshold catatonia. Some studies corroborate the model of an illness trajectory in which different mental disorders would be arranged along a continuum of severity until the development of catatonia. In such an illness pathway, autistic traits (AT) and borderline personality disorder (BPD) may represent important steps. In order to further explore the association between AT, BPD, and catatonia, the aim of this study was to compare catatonic spectrum symptoms and AT among patients with major depressive disorder (MDD), BPD, and healthy controls (CTL), also evaluating possible predictive dimensions of the different diagnoses. Methods: A total of 90 adults affected by BPD, 90 adults with a diagnosis of MDD, and 90 CTL, homogeneous in terms of gender and age, were recruited from six Italian university departments of psychiatry and assessed with the SCID-5-RV, the Catatonia Spectrum (CS), and the Adult Autism Subthreshold Autism Spectrum (AdAS Spectrum). Results: The total CS score was significantly higher in the BPD and MDD groups than in the CTL group, while the majority of CS domain scores were significantly higher in the BPD group than in the MDD group, which scored significantly higher than the CTL group. The total AdAS Spectrum score and the AdAS Spectrum domain scores were significantly higher in the BPD group than in the MDD group, which in turn scored significantly higher than the CTL group. The CS domains “psychomotor activity” and “impulsivity”, and AdAS Spectrum domains “verbal communication”, “empathy”, and “hyper-/hyporeactivity to sensory input” were associated with the risk of presenting a diagnosis of BPD. |
| first_indexed | 2024-03-11T00:05:10Z |
| format | Article |
| id | doaj.art-1e1ad8cb98c24ba9bb75537cd5c1e195 |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-11T00:05:10Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-1e1ad8cb98c24ba9bb75537cd5c1e1952023-11-19T00:26:49ZengMDPI AGBrain Sciences2076-34252023-08-01138117510.3390/brainsci13081175Autistic and Catatonic Spectrum Symptoms in Patients with Borderline Personality DisorderLiliana Dell’Osso0Giulia Amatori1Ivan Mirko Cremone2Enrico Massimetti3Benedetta Nardi4Davide Gravina5Francesca Benedetti6Maria Rosaria Anna Muscatello7Maurizio Pompili8Pierluigi Politi9Antonio Vita10Mario Maj11Barbara Carpita12Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, ItalyDepartment of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, ItalyDepartment of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, ItalyASST Bergamo Ovest, SSD Psychiatric Diagnosis and Treatment Service, 24047 Treviglio, ItalyDepartment of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, ItalyDepartment of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, ItalyDepartment of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, ItalyDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, 98124 Messina, ItalyDepartment of Neuroscience, Mental Health and Sense Organs, University of Roma “La Sapienza”, 00185 Roma, ItalyDepartment of Brain and Behavioral Sciences, University of Pavia, 27100 Pavia, ItalyDepartment of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, ItalyDepartment of Psychiatry, University of Naples “Luigi Vanvitelli”, 80138 Naples, ItalyDepartment of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, ItalyBackground: Recent literature has shown that a considerable percentage of patients with severe mental disorders can develop, over time, full-blown or subthreshold catatonia. Some studies corroborate the model of an illness trajectory in which different mental disorders would be arranged along a continuum of severity until the development of catatonia. In such an illness pathway, autistic traits (AT) and borderline personality disorder (BPD) may represent important steps. In order to further explore the association between AT, BPD, and catatonia, the aim of this study was to compare catatonic spectrum symptoms and AT among patients with major depressive disorder (MDD), BPD, and healthy controls (CTL), also evaluating possible predictive dimensions of the different diagnoses. Methods: A total of 90 adults affected by BPD, 90 adults with a diagnosis of MDD, and 90 CTL, homogeneous in terms of gender and age, were recruited from six Italian university departments of psychiatry and assessed with the SCID-5-RV, the Catatonia Spectrum (CS), and the Adult Autism Subthreshold Autism Spectrum (AdAS Spectrum). Results: The total CS score was significantly higher in the BPD and MDD groups than in the CTL group, while the majority of CS domain scores were significantly higher in the BPD group than in the MDD group, which scored significantly higher than the CTL group. The total AdAS Spectrum score and the AdAS Spectrum domain scores were significantly higher in the BPD group than in the MDD group, which in turn scored significantly higher than the CTL group. The CS domains “psychomotor activity” and “impulsivity”, and AdAS Spectrum domains “verbal communication”, “empathy”, and “hyper-/hyporeactivity to sensory input” were associated with the risk of presenting a diagnosis of BPD.https://www.mdpi.com/2076-3425/13/8/1175autism spectrum disordercatatoniaautism spectrumcatatonia spectrumborderline personality disorder |
| spellingShingle | Liliana Dell’Osso Giulia Amatori Ivan Mirko Cremone Enrico Massimetti Benedetta Nardi Davide Gravina Francesca Benedetti Maria Rosaria Anna Muscatello Maurizio Pompili Pierluigi Politi Antonio Vita Mario Maj Barbara Carpita Autistic and Catatonic Spectrum Symptoms in Patients with Borderline Personality Disorder Brain Sciences autism spectrum disorder catatonia autism spectrum catatonia spectrum borderline personality disorder |
| title | Autistic and Catatonic Spectrum Symptoms in Patients with Borderline Personality Disorder |
| title_full | Autistic and Catatonic Spectrum Symptoms in Patients with Borderline Personality Disorder |
| title_fullStr | Autistic and Catatonic Spectrum Symptoms in Patients with Borderline Personality Disorder |
| title_full_unstemmed | Autistic and Catatonic Spectrum Symptoms in Patients with Borderline Personality Disorder |
| title_short | Autistic and Catatonic Spectrum Symptoms in Patients with Borderline Personality Disorder |
| title_sort | autistic and catatonic spectrum symptoms in patients with borderline personality disorder |
| topic | autism spectrum disorder catatonia autism spectrum catatonia spectrum borderline personality disorder |
| url | https://www.mdpi.com/2076-3425/13/8/1175 |
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