Effect of renin-angiotensin -aldosterone system blockers on myocardial remodeling processes and risk for atrial fibrillation in patients with arterial hypertension

<p>The given review considers the mechanisms underlying the development and maintenance of atrial fibrillations (AF). It is noted that the processes of atrial fibrosis, ion channel remodeling, inflammation, apoptosis, impaired intercellular interactions, and myocardiocyte hypertrophy may give...

Full description

Bibliographic Details
Main Authors: O. M. Drapkina, M. V. Kostyukevich
Format: Article
Language:Russian
Published: ABV-press 2014-07-01
Series:Klinicist
Subjects:
Online Access:http://klinitsist.abvpress.ru/index.php/Klin/article/view/60
_version_ 1828081294105378816
author O. M. Drapkina
M. V. Kostyukevich
author_facet O. M. Drapkina
M. V. Kostyukevich
author_sort O. M. Drapkina
collection DOAJ
description <p>The given review considers the mechanisms underlying the development and maintenance of atrial fibrillations (AF). It is noted that the processes of atrial fibrosis, ion channel remodeling, inflammation, apoptosis, impaired intercellular interactions, and myocardiocyte hypertrophy may give rise to atrial structural and functional changes in AF. The efficacy of angiotensinonverting enzyme inhibitors and angiotensin receptor antagonists is justified in patients with left ventricular systolic dysfunction.</p>
first_indexed 2024-04-11T03:33:06Z
format Article
id doaj.art-1e1b04ee341b4f5db81bb7395f1c0a12
institution Directory Open Access Journal
issn 1818-8338
language Russian
last_indexed 2024-04-11T03:33:06Z
publishDate 2014-07-01
publisher ABV-press
record_format Article
series Klinicist
spelling doaj.art-1e1b04ee341b4f5db81bb7395f1c0a122023-01-02T05:57:52ZrusABV-pressKlinicist1818-83382014-07-0163-4737975Effect of renin-angiotensin -aldosterone system blockers on myocardial remodeling processes and risk for atrial fibrillation in patients with arterial hypertensionO. M. Drapkina0M. V. Kostyukevich1I.M. Sechenov First Moscow State Medical University, Ministry of Health of RussiaI.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia<p>The given review considers the mechanisms underlying the development and maintenance of atrial fibrillations (AF). It is noted that the processes of atrial fibrosis, ion channel remodeling, inflammation, apoptosis, impaired intercellular interactions, and myocardiocyte hypertrophy may give rise to atrial structural and functional changes in AF. The efficacy of angiotensinonverting enzyme inhibitors and angiotensin receptor antagonists is justified in patients with left ventricular systolic dysfunction.</p>http://klinitsist.abvpress.ru/index.php/Klin/article/view/60atrial fibrillationrenin-angiotensin-aldosterone systemmyocardial remodelingangiotensin-converting enzyme inhibitorsangiotensin receptor antagonists
spellingShingle O. M. Drapkina
M. V. Kostyukevich
Effect of renin-angiotensin -aldosterone system blockers on myocardial remodeling processes and risk for atrial fibrillation in patients with arterial hypertension
Klinicist
atrial fibrillation
renin-angiotensin-aldosterone system
myocardial remodeling
angiotensin-converting enzyme inhibitors
angiotensin receptor antagonists
title Effect of renin-angiotensin -aldosterone system blockers on myocardial remodeling processes and risk for atrial fibrillation in patients with arterial hypertension
title_full Effect of renin-angiotensin -aldosterone system blockers on myocardial remodeling processes and risk for atrial fibrillation in patients with arterial hypertension
title_fullStr Effect of renin-angiotensin -aldosterone system blockers on myocardial remodeling processes and risk for atrial fibrillation in patients with arterial hypertension
title_full_unstemmed Effect of renin-angiotensin -aldosterone system blockers on myocardial remodeling processes and risk for atrial fibrillation in patients with arterial hypertension
title_short Effect of renin-angiotensin -aldosterone system blockers on myocardial remodeling processes and risk for atrial fibrillation in patients with arterial hypertension
title_sort effect of renin angiotensin aldosterone system blockers on myocardial remodeling processes and risk for atrial fibrillation in patients with arterial hypertension
topic atrial fibrillation
renin-angiotensin-aldosterone system
myocardial remodeling
angiotensin-converting enzyme inhibitors
angiotensin receptor antagonists
url http://klinitsist.abvpress.ru/index.php/Klin/article/view/60
work_keys_str_mv AT omdrapkina effectofreninangiotensinaldosteronesystemblockersonmyocardialremodelingprocessesandriskforatrialfibrillationinpatientswitharterialhypertension
AT mvkostyukevich effectofreninangiotensinaldosteronesystemblockersonmyocardialremodelingprocessesandriskforatrialfibrillationinpatientswitharterialhypertension