Precision Oncology with Drugs Targeting the Replication Stress, ATR, and Schlafen 11

Precision Oncology with Drugs Targeting the Replication Stress, ATR, and Schlafen 11

Precision medicine aims to implement strategies based on the molecular features of tumors and optimized drug delivery to improve cancer diagnosis and treatment. DNA replication is a logical approach because it can be targeted by a broad range of anticancer drugs that are both clinically approved and...

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Bibliographic Details
Main Authors: Ukhyun Jo, Yasuhisa Murai, Naoko Takebe, Anish Thomas, Yves Pommier
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cancers
Subjects:
replication stress
ATR
schlafen 11
berzosertib
Camptothecin
cisplatin
Online Access:https://www.mdpi.com/2072-6694/13/18/4601

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