Optimal control in a model for Zika transmission with stratification by sex

This paper presents an optimal control strategy for the Zika virus disease with sexual transmission. A mathematical model for the transmission of the Zika virus is considered with three preventive measures as control, namely: the prevention of the sexual contagion with the use of condoms and the ori...

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Main Authors: Erick Manuel Delgado Moya, Aymée Marrero Severo
Format: Article
Language:Spanish
Published: Universidad Nacional de Trujillo 2020-12-01
Series:Selecciones Matemáticas
Subjects:
Online Access:https://revistas.unitru.edu.pe/index.php/SSMM/article/view/3091
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author Erick Manuel Delgado Moya
Aymée Marrero Severo
author_facet Erick Manuel Delgado Moya
Aymée Marrero Severo
author_sort Erick Manuel Delgado Moya
collection DOAJ
description This paper presents an optimal control strategy for the Zika virus disease with sexual transmission. A mathematical model for the transmission of the Zika virus is considered with three preventive measures as control, namely: the prevention of the sexual contagion with the use of condoms and the orientation in the transmission of Zika in the homosexual and heterosexual relations, the campaigns against vectors and the protection of the society regarding the contagion by mosquito bites. We examine the implementation of various combinations of the control strategies in order to determine the most cost-effective one. The necessary conditions for the optimal controls are determined using Pontryaguin’s maximum principle and the optimality problem is solved using Runge-Kutta fourth order scheme. Based on the computational results, we conclude that the most efficient control strategy is when it is applied on the infections in homosexual relationships combined with the control in the transmission by vectors.
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spelling doaj.art-1e1db40c767b4926b263423ffa29a9a42022-12-21T22:50:22ZspaUniversidad Nacional de TrujilloSelecciones Matemáticas2411-17832411-17832020-12-0170228930110.17268/sel.mat.2020.02.11Optimal control in a model for Zika transmission with stratification by sexErick Manuel Delgado Moya0https://orcid.org/0000-0001-5937-5374Aymée Marrero Severo1https://orcid.org/0000-0003-4823-0078IME- University of Sao Paulo, Rua do Matao, 1010, SP-BrazilMATCOM- University of Havana, Edificio Felipe Poey. San Lázaro y L. Colina Universitaria, Havana-CubaThis paper presents an optimal control strategy for the Zika virus disease with sexual transmission. A mathematical model for the transmission of the Zika virus is considered with three preventive measures as control, namely: the prevention of the sexual contagion with the use of condoms and the orientation in the transmission of Zika in the homosexual and heterosexual relations, the campaigns against vectors and the protection of the society regarding the contagion by mosquito bites. We examine the implementation of various combinations of the control strategies in order to determine the most cost-effective one. The necessary conditions for the optimal controls are determined using Pontryaguin’s maximum principle and the optimality problem is solved using Runge-Kutta fourth order scheme. Based on the computational results, we conclude that the most efficient control strategy is when it is applied on the infections in homosexual relationships combined with the control in the transmission by vectors.https://revistas.unitru.edu.pe/index.php/SSMM/article/view/3091modelsexual transmissionstrategyoptimal controlzika
spellingShingle Erick Manuel Delgado Moya
Aymée Marrero Severo
Optimal control in a model for Zika transmission with stratification by sex
Selecciones Matemáticas
model
sexual transmission
strategy
optimal control
zika
title Optimal control in a model for Zika transmission with stratification by sex
title_full Optimal control in a model for Zika transmission with stratification by sex
title_fullStr Optimal control in a model for Zika transmission with stratification by sex
title_full_unstemmed Optimal control in a model for Zika transmission with stratification by sex
title_short Optimal control in a model for Zika transmission with stratification by sex
title_sort optimal control in a model for zika transmission with stratification by sex
topic model
sexual transmission
strategy
optimal control
zika
url https://revistas.unitru.edu.pe/index.php/SSMM/article/view/3091
work_keys_str_mv AT erickmanueldelgadomoya optimalcontrolinamodelforzikatransmissionwithstratificationbysex
AT aymeemarrerosevero optimalcontrolinamodelforzikatransmissionwithstratificationbysex