Development of Sustainable Hydrophilic <i>Azadirachta indica</i> Loaded PVA Nanomembranes for Cosmetic Facemask Applications
Nanofiber-based facial masks have attracted the attention of modern cosmetic applications due to their controlled drug release, biocompatibility, and better efficiency. In this work, <i>Azadirachta indica</i> extract <i>(AI)</i> incorporated electrospun polyvinyl alcohol (PVA...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-01-01
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| Series: | Membranes |
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| Online Access: | https://www.mdpi.com/2077-0375/13/2/156 |
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| author | Rizwan Tahir Hasan B. Albargi Adnan Ahmad Muhammad Bilal Qadir Zubair Khaliq Ahsan Nazir Tanzeela Khalid Misbah Batool Salman Noshear Arshad Mohammed Jalalah Saeed A. Alsareii Farid A. Harraz |
| author_facet | Rizwan Tahir Hasan B. Albargi Adnan Ahmad Muhammad Bilal Qadir Zubair Khaliq Ahsan Nazir Tanzeela Khalid Misbah Batool Salman Noshear Arshad Mohammed Jalalah Saeed A. Alsareii Farid A. Harraz |
| author_sort | Rizwan Tahir |
| collection | DOAJ |
| description | Nanofiber-based facial masks have attracted the attention of modern cosmetic applications due to their controlled drug release, biocompatibility, and better efficiency. In this work, <i>Azadirachta indica</i> extract <i>(AI)</i> incorporated electrospun polyvinyl alcohol (PVA) nanofiber membrane was prepared to obtain a sustainable and hydrophilic facial mask. The electrospun <i>AI</i> incorporated PVA nanofiber membranes were characterized by scanning electron microscope, Ultraviolet-visible spectroscopy (UV-Vis) drug release, water absorption analysis, 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging, and antibacterial activity (qualitative and quantitative) at different PVA and <i>AI</i> concentrations. The optimized nanofiber of 376 ± 75 nm diameter was obtained at 8 wt/wt% PVA concentration and 100% <i>AI</i> extract. The <i>AI</i> nanoparticles of size range 50~250 nm in the extract were examined through a zeta sizer. The water absorption rate of ~660% and 17.24° water contact angle shows good hydrophilic nature and water absorbency of the nanofiber membrane. The UV-Vis also analyzed fast drug release of >70% in 5 min. The prepared membrane also exhibits 99.9% antibacterial activity against <i>Staphylococcus aureus</i> and has 79% antioxidant activity. Moreover, the membrane also had good mechanical properties (tensile strength 1.67 N, elongation 48%) and breathability (air permeability 15.24 mm/s). <i>AI</i>-incorporated nanofiber membrane can effectively be used for facial mask application. |
| first_indexed | 2024-03-11T08:27:02Z |
| format | Article |
| id | doaj.art-1e206ed825c5473fa7921c0e8c1cca41 |
| institution | Directory Open Access Journal |
| issn | 2077-0375 |
| language | English |
| last_indexed | 2024-03-11T08:27:02Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Membranes |
| spelling | doaj.art-1e206ed825c5473fa7921c0e8c1cca412023-11-16T22:02:07ZengMDPI AGMembranes2077-03752023-01-0113215610.3390/membranes13020156Development of Sustainable Hydrophilic <i>Azadirachta indica</i> Loaded PVA Nanomembranes for Cosmetic Facemask ApplicationsRizwan Tahir0Hasan B. Albargi1Adnan Ahmad2Muhammad Bilal Qadir3Zubair Khaliq4Ahsan Nazir5Tanzeela Khalid6Misbah Batool7Salman Noshear Arshad8Mohammed Jalalah9Saeed A. Alsareii10Farid A. Harraz11Department of Textile Engineering, National Textile University, Faisalabad 37610, PakistanPromising Centre for Sensors and Electronic Devices (PCSED), Advanced Materials and Nano-Research Centre, Najran University, Najran 11001, Saudi ArabiaDepartment of Textile Engineering, National Textile University, Faisalabad 37610, PakistanDepartment of Textile Engineering, National Textile University, Faisalabad 37610, PakistanDepartment of Materials, National Textile University, Faisalabad 37610, PakistanDepartment of Textile Engineering, National Textile University, Faisalabad 37610, PakistanDepartment of Dermatology, The University of Faisalabad, Faisalabad 38000, PakistanDepartment of Chemistry, University of Sargodha, Sargodha 40100, PakistanDepartment of Chemistry and Chemical Engineering, Lahore University of Management Sciences, Lahore 54792, PakistanPromising Centre for Sensors and Electronic Devices (PCSED), Advanced Materials and Nano-Research Centre, Najran University, Najran 11001, Saudi ArabiaPromising Centre for Sensors and Electronic Devices (PCSED), Advanced Materials and Nano-Research Centre, Najran University, Najran 11001, Saudi ArabiaPromising Centre for Sensors and Electronic Devices (PCSED), Advanced Materials and Nano-Research Centre, Najran University, Najran 11001, Saudi ArabiaNanofiber-based facial masks have attracted the attention of modern cosmetic applications due to their controlled drug release, biocompatibility, and better efficiency. In this work, <i>Azadirachta indica</i> extract <i>(AI)</i> incorporated electrospun polyvinyl alcohol (PVA) nanofiber membrane was prepared to obtain a sustainable and hydrophilic facial mask. The electrospun <i>AI</i> incorporated PVA nanofiber membranes were characterized by scanning electron microscope, Ultraviolet-visible spectroscopy (UV-Vis) drug release, water absorption analysis, 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging, and antibacterial activity (qualitative and quantitative) at different PVA and <i>AI</i> concentrations. The optimized nanofiber of 376 ± 75 nm diameter was obtained at 8 wt/wt% PVA concentration and 100% <i>AI</i> extract. The <i>AI</i> nanoparticles of size range 50~250 nm in the extract were examined through a zeta sizer. The water absorption rate of ~660% and 17.24° water contact angle shows good hydrophilic nature and water absorbency of the nanofiber membrane. The UV-Vis also analyzed fast drug release of >70% in 5 min. The prepared membrane also exhibits 99.9% antibacterial activity against <i>Staphylococcus aureus</i> and has 79% antioxidant activity. Moreover, the membrane also had good mechanical properties (tensile strength 1.67 N, elongation 48%) and breathability (air permeability 15.24 mm/s). <i>AI</i>-incorporated nanofiber membrane can effectively be used for facial mask application.https://www.mdpi.com/2077-0375/13/2/156electrospinningPVA nanofiber<i>Azadirachta indica</i>cosmeticfacial maskbiocompatible |
| spellingShingle | Rizwan Tahir Hasan B. Albargi Adnan Ahmad Muhammad Bilal Qadir Zubair Khaliq Ahsan Nazir Tanzeela Khalid Misbah Batool Salman Noshear Arshad Mohammed Jalalah Saeed A. Alsareii Farid A. Harraz Development of Sustainable Hydrophilic <i>Azadirachta indica</i> Loaded PVA Nanomembranes for Cosmetic Facemask Applications Membranes electrospinning PVA nanofiber <i>Azadirachta indica</i> cosmetic facial mask biocompatible |
| title | Development of Sustainable Hydrophilic <i>Azadirachta indica</i> Loaded PVA Nanomembranes for Cosmetic Facemask Applications |
| title_full | Development of Sustainable Hydrophilic <i>Azadirachta indica</i> Loaded PVA Nanomembranes for Cosmetic Facemask Applications |
| title_fullStr | Development of Sustainable Hydrophilic <i>Azadirachta indica</i> Loaded PVA Nanomembranes for Cosmetic Facemask Applications |
| title_full_unstemmed | Development of Sustainable Hydrophilic <i>Azadirachta indica</i> Loaded PVA Nanomembranes for Cosmetic Facemask Applications |
| title_short | Development of Sustainable Hydrophilic <i>Azadirachta indica</i> Loaded PVA Nanomembranes for Cosmetic Facemask Applications |
| title_sort | development of sustainable hydrophilic i azadirachta indica i loaded pva nanomembranes for cosmetic facemask applications |
| topic | electrospinning PVA nanofiber <i>Azadirachta indica</i> cosmetic facial mask biocompatible |
| url | https://www.mdpi.com/2077-0375/13/2/156 |
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