Serotonergic and dopaminergic mechanisms in graft-induced dyskinesia in a rat model of Parkinson's disease

Serotonergic and dopaminergic mechanisms in graft-induced dyskinesia in a rat model of Parkinson's disease

Dyskinesia seen in the off-state, referred as graft-induced dyskinesia (GID), has emerged as a serious complication induced by dopamine (DA) cell transplantation in parkinsonian patients. Although the mechanism underlying the appearance of GID is unknown, in a recent clinical study the partial 5-HT1...

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Bibliographic Details
Main Authors:	Eunju Shin, Joanna Garcia, Christian Winkler, Anders Björklund, Manolo Carta
Format:	Article
Language:	English
Published:	Elsevier 2012-09-01
Series:	Neurobiology of Disease
Subjects:	Graft-induced dyskinesia L-DOPA-induced dyskinesia Parkinson's disease Serotonin Dopamine D2 receptor Cell transplantation
Online Access:	http://www.sciencedirect.com/science/article/pii/S0969996112001271

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