Preparation and Performance of Silica-di-Block Polymer Hybrids for BSA-Resistance Coatings
A series of tem-responsive and protein-resistance property silica-di-block polymers SiO<sub>2</sub>-g-PMMA-b-P(PEGMA) hybrids are synthesized with methyl methacrylate (MMA) and poly (ethylene glycol) methyl ether methacrylate (PEGMA) by the surface-initiated atom transfer radical polymer...
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MDPI AG
2020-08-01
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| Online Access: | https://www.mdpi.com/1996-1944/13/16/3478 |
| _version_ | 1797559738106380288 |
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| author | Hongpu Huang Yefeng Feng Jia Qu |
| author_facet | Hongpu Huang Yefeng Feng Jia Qu |
| author_sort | Hongpu Huang |
| collection | DOAJ |
| description | A series of tem-responsive and protein-resistance property silica-di-block polymers SiO<sub>2</sub>-g-PMMA-b-P(PEGMA) hybrids are synthesized with methyl methacrylate (MMA) and poly (ethylene glycol) methyl ether methacrylate (PEGMA) by the surface-initiated atom transfer radical polymerization (SI-ATRP). The morphology in tetrahydrofuran (THF) solution, lower critical solution temperature (LCST), surface morphology, bovine serum albumin (BSA)-resistance property, and thermal stability of nanoparticles were analyzed. The results of <sup>1</sup>H-NMR, GPC, and TEM prove that the silica-di-block hybrids have been obtained. The silica-di-block hybrids shows the LCST (52–64 °C) in aqueous solution. The hybrid films casted by THF present distributed uniform granular bulges and the film surface is relatively smooth (Ra = 15.4 nm ~ 10.5 nm). The results of QCM-D showed that only a small amount of BSA protein(△<i>f</i> = 18.6 ~ 11.8 Hz) was adsorbed on the surface of the films. The result of XPS also demonstrated that only a small amount of BSA protein was absorbed onto the surface of the film (N% = 1.86). The TGA analyses indicate that the thermal decomposition temperature of hybrids is 288 °C. Thus, it is suggested that the hybrids are served as a suitable coating with BSA resistance property and thermal stability. |
| first_indexed | 2024-03-10T17:49:34Z |
| format | Article |
| id | doaj.art-1e25546e415a4ed7aa50f162ca99be01 |
| institution | Directory Open Access Journal |
| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-03-10T17:49:34Z |
| publishDate | 2020-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Materials |
| spelling | doaj.art-1e25546e415a4ed7aa50f162ca99be012023-11-20T09:22:52ZengMDPI AGMaterials1996-19442020-08-011316347810.3390/ma13163478Preparation and Performance of Silica-di-Block Polymer Hybrids for BSA-Resistance CoatingsHongpu Huang0Yefeng Feng1Jia Qu2School of Materials Science and Engineering, Yangtze Normal University, Chongqing 408100, ChinaSchool of Materials Science and Engineering, Yangtze Normal University, Chongqing 408100, ChinaShaanxi Key Laboratory of Comprehensive Utilization of Tailings Resources, Shaanxi Engineering Research Center for Mineral Resources Clean & Efficient Conversion and New Materials, Shangluo University, Shangluo 726000, Shaanxi, ChinaA series of tem-responsive and protein-resistance property silica-di-block polymers SiO<sub>2</sub>-g-PMMA-b-P(PEGMA) hybrids are synthesized with methyl methacrylate (MMA) and poly (ethylene glycol) methyl ether methacrylate (PEGMA) by the surface-initiated atom transfer radical polymerization (SI-ATRP). The morphology in tetrahydrofuran (THF) solution, lower critical solution temperature (LCST), surface morphology, bovine serum albumin (BSA)-resistance property, and thermal stability of nanoparticles were analyzed. The results of <sup>1</sup>H-NMR, GPC, and TEM prove that the silica-di-block hybrids have been obtained. The silica-di-block hybrids shows the LCST (52–64 °C) in aqueous solution. The hybrid films casted by THF present distributed uniform granular bulges and the film surface is relatively smooth (Ra = 15.4 nm ~ 10.5 nm). The results of QCM-D showed that only a small amount of BSA protein(△<i>f</i> = 18.6 ~ 11.8 Hz) was adsorbed on the surface of the films. The result of XPS also demonstrated that only a small amount of BSA protein was absorbed onto the surface of the film (N% = 1.86). The TGA analyses indicate that the thermal decomposition temperature of hybrids is 288 °C. Thus, it is suggested that the hybrids are served as a suitable coating with BSA resistance property and thermal stability.https://www.mdpi.com/1996-1944/13/16/3478silica-di-block hybridsLCSTsurface propertiesBSA resistancecoating |
| spellingShingle | Hongpu Huang Yefeng Feng Jia Qu Preparation and Performance of Silica-di-Block Polymer Hybrids for BSA-Resistance Coatings Materials silica-di-block hybrids LCST surface properties BSA resistance coating |
| title | Preparation and Performance of Silica-di-Block Polymer Hybrids for BSA-Resistance Coatings |
| title_full | Preparation and Performance of Silica-di-Block Polymer Hybrids for BSA-Resistance Coatings |
| title_fullStr | Preparation and Performance of Silica-di-Block Polymer Hybrids for BSA-Resistance Coatings |
| title_full_unstemmed | Preparation and Performance of Silica-di-Block Polymer Hybrids for BSA-Resistance Coatings |
| title_short | Preparation and Performance of Silica-di-Block Polymer Hybrids for BSA-Resistance Coatings |
| title_sort | preparation and performance of silica di block polymer hybrids for bsa resistance coatings |
| topic | silica-di-block hybrids LCST surface properties BSA resistance coating |
| url | https://www.mdpi.com/1996-1944/13/16/3478 |
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