The Hippo–YAP/TAZ Signaling Pathway in Intestinal Self-Renewal and Regeneration After Injury

The Hippo–YAP/TAZ Signaling Pathway in Intestinal Self-Renewal and Regeneration After Injury

The Hippo pathway and its downstream effectors, the transcriptional coactivators Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ), control stem cell fate and cell proliferation and differentiation and are essential for tissue self-renewal and regeneration. YA...

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Bibliographic Details
Main Authors: Feihong Deng, Zengrong Wu, Fei Zou, Su Wang, Xuehong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
hippo–YAP/TAZ pathway
intestinal self-renewal
intestinal regeneration
intestinal stem cell
inflammatory bowel disease
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.894737/full

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