RSV-induced changes in a 3-dimensional organoid model of human fetal lungs.
We have shown that respiratory syncytial virus (RSV) can spread hematogenously from infected airways of a pregnant woman to the developing fetal lungs in utero. This study sought to measure RSV replication, cytopathic effects, and protein expression in human lung organoids (HLOs) reproducing archite...
Main Authors: | Terri J Harford, Fariba Rezaee, Briana R Dye, Jia Fan, Jason R Spence, Giovanni Piedimonte |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0265094 |
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