A Comparative Study of Corneal Topography in Children with Autism Spectrum Disorder: A Cross-Sectional Study
Purpose: To investigate the corneal characteristics in individuals with autism spectrum disorder (ASD) and age-matched typical development (TD) participants. Methods: This cross-sectional, clinically based study compared children with ASD to age-matched TD participants. Corneal topography was measur...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-01-01
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| Series: | Vision |
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| Online Access: | https://www.mdpi.com/2411-5150/5/1/4 |
| _version_ | 1797411072641073152 |
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| author | Maha A. ALGarzaie Ali M. Alsaqr |
| author_facet | Maha A. ALGarzaie Ali M. Alsaqr |
| author_sort | Maha A. ALGarzaie |
| collection | DOAJ |
| description | Purpose: To investigate the corneal characteristics in individuals with autism spectrum disorder (ASD) and age-matched typical development (TD) participants. Methods: This cross-sectional, clinically based study compared children with ASD to age-matched TD participants. Corneal topography was measured with a portable EyeSys Vista system. The distance visual acuity (VA) and the contrast sensitivity (CS) were determined. The refractive error (RE) was assessed using a 2WIN autorefractometer. Results: A total of 31 children with ASD (mean age: 12.78 ± 4.49 years), and 60 participants with TD (mean age: 13.65 ± 3.56 years) were recruited. The two groups were similar in age (t = −2.084, <i>p</i> = 0.075) and VA (t = −0.35, <i>p</i> = 0.32). Most of the children with ASD had a significant amount of refractive errors (REs; range: +5.25 to −5.50 DS), and astigmatism was dominant (range: −0.25 to −4.50 DC). There was no statistically significant difference between both groups in terms of average corneal power (t = 1.12, <i>p</i> = 0.39). The children with ASD and participants with TD also did not differ significantly in terms of corneal shape descriptors (<i>p</i> > 0.05), such as corneal asphericity, inferior superior index, opposite sector index, and differential sector index. The spherical equivalent did not differ significantly between the ASD participants and participants with TD (t = 1.15, <i>p</i> = 0.15). There was a significant difference (<i>p</i> < 0.05) in the astigmatism component between the ASD participants and the participants with TD. |
| first_indexed | 2024-03-09T04:39:43Z |
| format | Article |
| id | doaj.art-1e2a845fa7c54c46806bde1b6083e0f8 |
| institution | Directory Open Access Journal |
| issn | 2411-5150 |
| language | English |
| last_indexed | 2024-03-09T04:39:43Z |
| publishDate | 2021-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vision |
| spelling | doaj.art-1e2a845fa7c54c46806bde1b6083e0f82023-12-03T13:21:37ZengMDPI AGVision2411-51502021-01-0151410.3390/vision5010004A Comparative Study of Corneal Topography in Children with Autism Spectrum Disorder: A Cross-Sectional StudyMaha A. ALGarzaie0Ali M. Alsaqr1Department of Optometry, Prince Sultan Military Medical City, Riyadh 091510, Saudi ArabiaDepartment of Optometry, College of Applied Medical Sciences, King Saud University, Riyadh 091510, Saudi ArabiaPurpose: To investigate the corneal characteristics in individuals with autism spectrum disorder (ASD) and age-matched typical development (TD) participants. Methods: This cross-sectional, clinically based study compared children with ASD to age-matched TD participants. Corneal topography was measured with a portable EyeSys Vista system. The distance visual acuity (VA) and the contrast sensitivity (CS) were determined. The refractive error (RE) was assessed using a 2WIN autorefractometer. Results: A total of 31 children with ASD (mean age: 12.78 ± 4.49 years), and 60 participants with TD (mean age: 13.65 ± 3.56 years) were recruited. The two groups were similar in age (t = −2.084, <i>p</i> = 0.075) and VA (t = −0.35, <i>p</i> = 0.32). Most of the children with ASD had a significant amount of refractive errors (REs; range: +5.25 to −5.50 DS), and astigmatism was dominant (range: −0.25 to −4.50 DC). There was no statistically significant difference between both groups in terms of average corneal power (t = 1.12, <i>p</i> = 0.39). The children with ASD and participants with TD also did not differ significantly in terms of corneal shape descriptors (<i>p</i> > 0.05), such as corneal asphericity, inferior superior index, opposite sector index, and differential sector index. The spherical equivalent did not differ significantly between the ASD participants and participants with TD (t = 1.15, <i>p</i> = 0.15). There was a significant difference (<i>p</i> < 0.05) in the astigmatism component between the ASD participants and the participants with TD.https://www.mdpi.com/2411-5150/5/1/4autismcorneal powercorneal descriptorskeratoconuscorneal shape |
| spellingShingle | Maha A. ALGarzaie Ali M. Alsaqr A Comparative Study of Corneal Topography in Children with Autism Spectrum Disorder: A Cross-Sectional Study Vision autism corneal power corneal descriptors keratoconus corneal shape |
| title | A Comparative Study of Corneal Topography in Children with Autism Spectrum Disorder: A Cross-Sectional Study |
| title_full | A Comparative Study of Corneal Topography in Children with Autism Spectrum Disorder: A Cross-Sectional Study |
| title_fullStr | A Comparative Study of Corneal Topography in Children with Autism Spectrum Disorder: A Cross-Sectional Study |
| title_full_unstemmed | A Comparative Study of Corneal Topography in Children with Autism Spectrum Disorder: A Cross-Sectional Study |
| title_short | A Comparative Study of Corneal Topography in Children with Autism Spectrum Disorder: A Cross-Sectional Study |
| title_sort | comparative study of corneal topography in children with autism spectrum disorder a cross sectional study |
| topic | autism corneal power corneal descriptors keratoconus corneal shape |
| url | https://www.mdpi.com/2411-5150/5/1/4 |
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