Alzheimer's disease as an autoimmune disorder of innate immunity endogenously modulated by tryptophan metabolites

Alzheimer's disease as an autoimmune disorder of innate immunity endogenously modulated by tryptophan metabolites

Abstract Introduction Alzheimer's disease (AD) is characterized by neurotoxic immuno‐inflammation concomitant with cytotoxic oligomerization of amyloid beta (Aβ) and tau, culminating in concurrent, interdependent immunopathic and proteopathic pathogeneses. Methods We performed a comprehensive s...

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Autors principals: Felix S. Meier‐Stephenson, Vanessa C. Meier‐Stephenson, Michael D. Carter, Autumn R. Meek, Yanfei Wang, Luzhe Pan, Qiangwei Chen, Sheila Jacobo, Fan Wu, Erhu Lu, Gordon A. Simms, Laural Fisher, Alaina J. McGrath, Virgil Fermo, Christopher J. Barden, Harman D.S. Clair, Todd N. Galloway, Arun Yadav, Valérie Campágna‐Slater, Mark Hadden, Mark Reed, Marcia Taylor, Brendan Kelly, Elena Diez‐Cecilia, Igri Kolaj, Clarissa Santos, Imindu Liyanage, Braden Sweeting, Paul Stafford, Robert Boudreau, G. Andrew Reid, Ryan S. Noyce, Leanne Stevens, Agnieszka Staniszewski, Hong Zhang, Mamidanna R. V. S. Murty, Pascale Lemaire, Solenne Chardonnet, Christopher D. Richardson, Valérie Gabelica, Edwin DePauw, Richard Brown, Sultan Darvesh, Ottavio Arancio, Donald F. Weaver
Format: Article
Idioma:English
Publicat: Wiley 2022-01-01
Col·lecció:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Matèries:
Alzheimer's disease
amyloid beta
antimicrobial peptide
arginine
autoimmune
cytokine
Accés en línia:https://doi.org/10.1002/trc2.12283

Internet

https://doi.org/10.1002/trc2.12283

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