Unleashed Actin Assembly in Capping Protein-Deficient B16-F1 Cells Enables Identification of Multiple Factors Contributing to Filopodium Formation

Background: Filopodia are dynamic, finger-like actin-filament bundles that overcome membrane tension by forces generated through actin polymerization at their tips to allow extension of these structures a few microns beyond the cell periphery. Actin assembly of these protrusions is regulated by acce...

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Bibliographic Details
Main Authors: Jens Ingo Hein, Jonas Scholz, Sarah Körber, Thomas Kaufmann, Jan Faix
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/6/890

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