Effect of combination sildenafil and gemfibrozil on cisplatin-induced nephrotoxicity; role of heme oxygenase-1

Effect of combination sildenafil and gemfibrozil on cisplatin-induced nephrotoxicity; role of heme oxygenase-1

Background/aim: Cisplatin-induced nephrotoxicity in large proportion of patients. The aim of this work is to clarify the effect of combination of sildenafil and gemfibrozil on cisplatin-induced nephrotoxicity either before or after cisplatin treatment and determination of nephrotoxicity predictors a...

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Bibliographic Details
Main Authors: Safaa Behiry, Ahmed Rabie, Mahmoud Kora, Wesam Ismail, Dina Sabry, Ahmed Zahran
Format: Article
Language:English
Published: Taylor & Francis Group 2018-10-01
Series:Renal Failure
Subjects:
Acute kidney injury
cisplatin nephrotoxicity
gemfibrozil
heme oxygenase-1
oxidative stress and sildenafil
Online Access:http://dx.doi.org/10.1080/0886022X.2018.1455596

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