Keratolysis exfoliativa-like eruption induced by ranolazione

Dermatoses affecting palms may represent a dermatologic challenge from both the diagnostic, and therapeutic point of view. Patients with supposedly occupational dermatitis can spend months or even years in a frustrating attempt to avoid contact with possible irritants or allergens. To underline the...

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Bibliographic Details
Main Authors: Elena Pierobon, Lerica Germi, Andrea Sechi, Giampaolo Trevisan, Elena Pezzolo, Claudio Feliciani, Luigi Naldi
Format: Article
Language:English
Published: PAGEPress Publications 2021-10-01
Series:Dermatology Reports
Subjects:
Online Access:https://www.pagepress.org/journals/index.php/dr/article/view/9264
Description
Summary:Dermatoses affecting palms may represent a dermatologic challenge from both the diagnostic, and therapeutic point of view. Patients with supposedly occupational dermatitis can spend months or even years in a frustrating attempt to avoid contact with possible irritants or allergens. To underline the importance of a thorough unbiased analysis of the patient’s history and clinical features, we present the iconic case of a bricklayer affected by a chronic, disabling desquamation of palms which in the end was classified as keratolysis exfoliativa (KE) attributed to ranolazine-intake, an antianginal drug. To the best of our knowledge, this specific adverse effect of drug-induced KE of palms has never been reported before in association with ranolazine.
ISSN:2036-7392
2036-7406