Antibacterial Activity of Honey Against Bacteria Isolated from Respiratory Tract Infections

Antibacterial Activity of Honey Against Bacteria Isolated from Respiratory Tract Infections

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Objective This study aims to verify any antibacterial activity of honey against bacteria concerned with Respiratory Tract Infections in Karachi, Pakistan. Methodology Three brands of commercial honey, one rude and two processed were used to determine their antibacterial activity against four...

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Bibliographic Details
Main Authors: Farhan Essaa Abdullah, Kiran Afab, Rabia Khanum, Sidrah Sohail Khan
Format: Article
Language:English
Published: Dow University of Health Sciences 2012-12-01
Series:Journal of the Dow University of Health Sciences
Subjects:
Honey
antibacterial sensitivity
respiratory infections
Online Access:https://jduhs.com/index.php/jduhs/article/view/1485
Description
Summary:Objective This study aims to verify any antibacterial activity of honey against bacteria concerned with Respiratory Tract Infections in Karachi, Pakistan. Methodology Three brands of commercial honey, one rude and two processed were used to determine their antibacterial activity against four bacterial species, Klebsiella pneumoniae (n=56), Pneumococci (n=34), Pseudomonas aeruginosa (n=16), and Staphylococcus aureus (n=20), isolated from Sputum and Throat swab specimens. The cork-bore method was employed using Mueller-Hinton agar, and the inhibition zones around the wells containing 20%w/v honey solutions were assessed using Imipenem disc (30ug) as the standard of antibacterial activity. Data was analyzed using SPSS 16.0. Results Significant antibacterial activity of honey was observed against the 4 RTI isolates, with higher sensitivities for ProcS (Salman s Honey) and Crude sample. The Crude sample yielded relatively superior inhibition zones than the other two specimens; it affected all 34 (100%) of Pneumococci, 29 of 56 (52%) Klebsiellae, 14 of 20 (70%) Staphylococci and 4 of 16 (25%) Pseudomonas isolates. Pneumococci were significantly more sensitive to all 3 honey specimens, while pseudomonas were least sensitive compared to other isolates. Conclusion Samples of honey showed promising in vitro antibacterial activity on some RTI isolates.
ISSN:1995-2198
2410-2180

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