Fas Ligand-mediated cytotoxicity of CD4+ T cells during chronic retrovirus infection

Fas Ligand-mediated cytotoxicity of CD4+ T cells during chronic retrovirus infection

Abstract CD4+ helper T cells and cytotoxic CD8+ T cells are key players for adaptive immune responses against acute infections with retroviruses. Similar to textbook knowledge the most important function of CD4+ T cells during an acute retrovirus infection seems to be their helper function for other...

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Bibliographic Details
Main Authors: Anna Malyshkina, Elisabeth Littwitz-Salomon, Kathrin Sutter, Gennadiy Zelinskyy, Sonja Windmann, Simone Schimmer, Annette Paschen, Hendrik Streeck, Kim J. Hasenkrug, Ulf Dittmer
Format: Article
Language:English
Published: Nature Portfolio 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-08578-7

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