Assessing the Vaccine Efficacy in Health Care Providers for Combating the COVID-19 Infection: Results from Tertiary Cancer Care Centre

Due to the COVID-19 pandemic’s rapid expansion, the creation of vaccines is crucial for lowering disease transmission. Therefore, to determine the safety and efficacy of the vaccine against symptomatic illness and to evaluate breakthrough infections, those who received single or both the doses of va...

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Main Authors: Shalini Agnihotri, Anurag Mehta, Anurag Sharma
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:COVID
Subjects:
Online Access:https://www.mdpi.com/2673-8112/3/2/18
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author Shalini Agnihotri
Anurag Mehta
Anurag Sharma
author_facet Shalini Agnihotri
Anurag Mehta
Anurag Sharma
author_sort Shalini Agnihotri
collection DOAJ
description Due to the COVID-19 pandemic’s rapid expansion, the creation of vaccines is crucial for lowering disease transmission. Therefore, to determine the safety and efficacy of the vaccine against symptomatic illness and to evaluate breakthrough infections, those who received single or both the doses of vaccine against COVID-19 infection. A retrospective observational study was carried out on vaccine efficacy and the incidence of the breakthrough infections among the heath care workers, support staff and administrative staff. Out of 599 fully vaccinated health care workers, those who tested COVID-19 positive post-vaccination only 1.16% developed a severe illness that necessitates hospitalization. This study reflects a significant vaccine efficacy of 81.3% after a complete dose of vaccination and protection of 76.9% after one standard dose against symptomatic disease. The frequency of COVID-19 vaccine breakthrough is very low, which means that COVID-19 vaccines are highly effective at preventing COVID-19, particularly when it comes to severity.
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spelling doaj.art-1e41e6e675544959a2c6312b9fb3a4f92023-11-16T19:54:07ZengMDPI AGCOVID2673-81122023-02-013223824510.3390/covid3020018Assessing the Vaccine Efficacy in Health Care Providers for Combating the COVID-19 Infection: Results from Tertiary Cancer Care CentreShalini Agnihotri0Anurag Mehta1Anurag Sharma2Rajiv Gandhi Cancer Institute and Research Centre, Delhi 110085, IndiaRajiv Gandhi Cancer Institute and Research Centre, Delhi 110085, IndiaRajiv Gandhi Cancer Institute and Research Centre, Delhi 110085, IndiaDue to the COVID-19 pandemic’s rapid expansion, the creation of vaccines is crucial for lowering disease transmission. Therefore, to determine the safety and efficacy of the vaccine against symptomatic illness and to evaluate breakthrough infections, those who received single or both the doses of vaccine against COVID-19 infection. A retrospective observational study was carried out on vaccine efficacy and the incidence of the breakthrough infections among the heath care workers, support staff and administrative staff. Out of 599 fully vaccinated health care workers, those who tested COVID-19 positive post-vaccination only 1.16% developed a severe illness that necessitates hospitalization. This study reflects a significant vaccine efficacy of 81.3% after a complete dose of vaccination and protection of 76.9% after one standard dose against symptomatic disease. The frequency of COVID-19 vaccine breakthrough is very low, which means that COVID-19 vaccines are highly effective at preventing COVID-19, particularly when it comes to severity.https://www.mdpi.com/2673-8112/3/2/18COVID-19vaccinevaccine efficacybreakthroughinfection
spellingShingle Shalini Agnihotri
Anurag Mehta
Anurag Sharma
Assessing the Vaccine Efficacy in Health Care Providers for Combating the COVID-19 Infection: Results from Tertiary Cancer Care Centre
COVID
COVID-19
vaccine
vaccine efficacy
breakthrough
infection
title Assessing the Vaccine Efficacy in Health Care Providers for Combating the COVID-19 Infection: Results from Tertiary Cancer Care Centre
title_full Assessing the Vaccine Efficacy in Health Care Providers for Combating the COVID-19 Infection: Results from Tertiary Cancer Care Centre
title_fullStr Assessing the Vaccine Efficacy in Health Care Providers for Combating the COVID-19 Infection: Results from Tertiary Cancer Care Centre
title_full_unstemmed Assessing the Vaccine Efficacy in Health Care Providers for Combating the COVID-19 Infection: Results from Tertiary Cancer Care Centre
title_short Assessing the Vaccine Efficacy in Health Care Providers for Combating the COVID-19 Infection: Results from Tertiary Cancer Care Centre
title_sort assessing the vaccine efficacy in health care providers for combating the covid 19 infection results from tertiary cancer care centre
topic COVID-19
vaccine
vaccine efficacy
breakthrough
infection
url https://www.mdpi.com/2673-8112/3/2/18
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