Volume of white matter hyperintensities increases with blood pressure in patients with hypertension
Objective Hypertension is a risk factor for development of white matter hyperintensities (WMHs). However, the relationship between hypertension and WMHs remains obscure. We sought to clarify this relationship using clinical data from different regions of China. Methods We analyzed the data of 333 pa...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2019-08-01
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| Series: | Journal of International Medical Research |
| Online Access: | https://doi.org/10.1177/0300060519858023 |
| _version_ | 1818723367876820992 |
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| author | Yu Zhao Zunyu Ke Wenbo He Zhiyou Cai |
| author_facet | Yu Zhao Zunyu Ke Wenbo He Zhiyou Cai |
| author_sort | Yu Zhao |
| collection | DOAJ |
| description | Objective Hypertension is a risk factor for development of white matter hyperintensities (WMHs). However, the relationship between hypertension and WMHs remains obscure. We sought to clarify this relationship using clinical data from different regions of China. Methods We analyzed the data of 333 patients with WMHs in this study. All included patients underwent conventional magnetic resonance imaging (MRI) examination. A primary diagnosis of WMHs was made according to MRI findings. The volume burden of WMHs was investigated using the Fazekas scale, which is widely used to rate the degree of WMHs. We conducted retrospective clinical analysis of the data in this study. Results Our findings showed that WMHs in patients with hypertension were associated with diabetes, cardiovascular diseases, history of cerebral infarct, and plasma glucose and triglyceride levels. Fazekas scale scores for WMHs increased with increased blood pressure values in patients with hypertension. Conclusion This analysis indicates that hypertension is an independent contributor to the prevalence and severity of WMHs. |
| first_indexed | 2024-12-17T21:09:24Z |
| format | Article |
| id | doaj.art-1e41eed9a87b4419bc98257ca7b35743 |
| institution | Directory Open Access Journal |
| issn | 0300-0605 1473-2300 |
| language | English |
| last_indexed | 2024-12-17T21:09:24Z |
| publishDate | 2019-08-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of International Medical Research |
| spelling | doaj.art-1e41eed9a87b4419bc98257ca7b357432022-12-21T21:32:30ZengSAGE PublishingJournal of International Medical Research0300-06051473-23002019-08-014710.1177/0300060519858023Volume of white matter hyperintensities increases with blood pressure in patients with hypertensionYu ZhaoZunyu KeWenbo HeZhiyou CaiObjective Hypertension is a risk factor for development of white matter hyperintensities (WMHs). However, the relationship between hypertension and WMHs remains obscure. We sought to clarify this relationship using clinical data from different regions of China. Methods We analyzed the data of 333 patients with WMHs in this study. All included patients underwent conventional magnetic resonance imaging (MRI) examination. A primary diagnosis of WMHs was made according to MRI findings. The volume burden of WMHs was investigated using the Fazekas scale, which is widely used to rate the degree of WMHs. We conducted retrospective clinical analysis of the data in this study. Results Our findings showed that WMHs in patients with hypertension were associated with diabetes, cardiovascular diseases, history of cerebral infarct, and plasma glucose and triglyceride levels. Fazekas scale scores for WMHs increased with increased blood pressure values in patients with hypertension. Conclusion This analysis indicates that hypertension is an independent contributor to the prevalence and severity of WMHs.https://doi.org/10.1177/0300060519858023 |
| spellingShingle | Yu Zhao Zunyu Ke Wenbo He Zhiyou Cai Volume of white matter hyperintensities increases with blood pressure in patients with hypertension Journal of International Medical Research |
| title | Volume of white matter hyperintensities increases with blood pressure in patients with hypertension |
| title_full | Volume of white matter hyperintensities increases with blood pressure in patients with hypertension |
| title_fullStr | Volume of white matter hyperintensities increases with blood pressure in patients with hypertension |
| title_full_unstemmed | Volume of white matter hyperintensities increases with blood pressure in patients with hypertension |
| title_short | Volume of white matter hyperintensities increases with blood pressure in patients with hypertension |
| title_sort | volume of white matter hyperintensities increases with blood pressure in patients with hypertension |
| url | https://doi.org/10.1177/0300060519858023 |
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