Optimization of nutrient utilization efficiency and productivity for algal cultures under light and dark cycles using genome-scale model process control

Abstract Algal cultivations are strongly influenced by light and dark cycles. In this study, genome-scale metabolic models were applied to optimize nutrient supply during alternating light and dark cycles of Chlorella vulgaris. This approach lowered the glucose requirement by 75% and nitrate require...

Полное описание

Библиографические подробности
Главные авторы: Chien-Ting Li, Richard Eng, Cristal Zuniga, Kai-Wen Huang, Yiqun Chen, Karsten Zengler, Michael J. Betenbaugh
Формат: Статья
Язык:English
Опубликовано: Nature Portfolio 2023-03-01
Серии:npj Systems Biology and Applications
Online-ссылка:https://doi.org/10.1038/s41540-022-00260-7