Mortality through associated illnesses in tuberculosis patients and post-mortem pulmonary tuberculosis diagnosis in Chisinau

Background: The main cause of death of tuberculosis patients is the progression of tuberculosis, but the presence of associated diseases decreases the outcome of treatment of both the underlying and the associated disease, and the latter is the cause of death. Thus, reducing the mortality of tubercu...

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Main Author: Vasile Popa
Format: Article
Language:English
Published: Scientific Medical Association of Moldova 2017-10-01
Series:The Moldovan Medical Journal
Subjects:
Online Access:http://moldmedjournal.md/wp-content/uploads/2018/10/moldmedjournal-2017-603-popa-full-article.pdf
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author Vasile Popa
author_facet Vasile Popa
author_sort Vasile Popa
collection DOAJ
description Background: The main cause of death of tuberculosis patients is the progression of tuberculosis, but the presence of associated diseases decreases the outcome of treatment of both the underlying and the associated disease, and the latter is the cause of death. Thus, reducing the mortality of tuberculosis patients can be solved by increasing the therapeutic success rate of tuberculosis as well as associated diseases. Material and methods: A selective, descriptive and retrospective study was carried out in 3 time periods: period I (2001-2003) – implementation of the DOTS strategy in Chisinau municipality; period II (2007-2009) characterized by the tense epidemiological situation, the high TB mortality indicator and the implementation of the STOP TB strategy; period III (2013-2015) characterized by a shift to “End TB” strategy and a marked decrease in tuberculosis mortality. Results: Analyzing the reference periods, we found that in the 1st period 1/4 of the total deaths were caused by tuberculosis, associated diseases and other causes, in the 2nd period there was a decrease in the number of deaths, and in the 3rd period there was about 2 times increase in the number of deaths. Conclusions: The most common concomitant diseases were: oncological, cardiovascular, hepatic cirrhosis and other causes. The number of deaths with the post-mortem tuberculosis diagnosis was decreasing; half of them occurred at home, ½ of the deceased were without a stable place of living.
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spelling doaj.art-1e44cffce2cb4530be1ee27744ef198f2022-12-22T01:32:05ZengScientific Medical Association of MoldovaThe Moldovan Medical Journal2537-63732537-63812017-10-01603101610.5281/zenodo.1051120Mortality through associated illnesses in tuberculosis patients and post-mortem pulmonary tuberculosis diagnosis in ChisinauVasile Popa0Municipal Clinical Hospital of Phthisiopneumology, Chisinau, the Republic of MoldovaBackground: The main cause of death of tuberculosis patients is the progression of tuberculosis, but the presence of associated diseases decreases the outcome of treatment of both the underlying and the associated disease, and the latter is the cause of death. Thus, reducing the mortality of tuberculosis patients can be solved by increasing the therapeutic success rate of tuberculosis as well as associated diseases. Material and methods: A selective, descriptive and retrospective study was carried out in 3 time periods: period I (2001-2003) – implementation of the DOTS strategy in Chisinau municipality; period II (2007-2009) characterized by the tense epidemiological situation, the high TB mortality indicator and the implementation of the STOP TB strategy; period III (2013-2015) characterized by a shift to “End TB” strategy and a marked decrease in tuberculosis mortality. Results: Analyzing the reference periods, we found that in the 1st period 1/4 of the total deaths were caused by tuberculosis, associated diseases and other causes, in the 2nd period there was a decrease in the number of deaths, and in the 3rd period there was about 2 times increase in the number of deaths. Conclusions: The most common concomitant diseases were: oncological, cardiovascular, hepatic cirrhosis and other causes. The number of deaths with the post-mortem tuberculosis diagnosis was decreasing; half of them occurred at home, ½ of the deceased were without a stable place of living.http://moldmedjournal.md/wp-content/uploads/2018/10/moldmedjournal-2017-603-popa-full-article.pdfpulmonary tuberculosisassociated pathologiesmortalitypost-mortem diagnosis
spellingShingle Vasile Popa
Mortality through associated illnesses in tuberculosis patients and post-mortem pulmonary tuberculosis diagnosis in Chisinau
The Moldovan Medical Journal
pulmonary tuberculosis
associated pathologies
mortality
post-mortem diagnosis
title Mortality through associated illnesses in tuberculosis patients and post-mortem pulmonary tuberculosis diagnosis in Chisinau
title_full Mortality through associated illnesses in tuberculosis patients and post-mortem pulmonary tuberculosis diagnosis in Chisinau
title_fullStr Mortality through associated illnesses in tuberculosis patients and post-mortem pulmonary tuberculosis diagnosis in Chisinau
title_full_unstemmed Mortality through associated illnesses in tuberculosis patients and post-mortem pulmonary tuberculosis diagnosis in Chisinau
title_short Mortality through associated illnesses in tuberculosis patients and post-mortem pulmonary tuberculosis diagnosis in Chisinau
title_sort mortality through associated illnesses in tuberculosis patients and post mortem pulmonary tuberculosis diagnosis in chisinau
topic pulmonary tuberculosis
associated pathologies
mortality
post-mortem diagnosis
url http://moldmedjournal.md/wp-content/uploads/2018/10/moldmedjournal-2017-603-popa-full-article.pdf
work_keys_str_mv AT vasilepopa mortalitythroughassociatedillnessesintuberculosispatientsandpostmortempulmonarytuberculosisdiagnosisinchisinau