Development of Dextran-Coated Magnetic Nanoparticles Loaded with Protocatechuic Acid for Vascular Inflammation Therapy

Development of Dextran-Coated Magnetic Nanoparticles Loaded with Protocatechuic Acid for Vascular Inflammation Therapy

Vascular inflammation plays a crucial role in the progression of various pathologies, including atherosclerosis (AS), and thus it has become an attractive therapeutic target. The protocatechuic acid (PCA), one of the main metabolites of complex polyphenols, is endowed with anti-inflammatory activity...

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Bibliographic Details
Main Authors: Maria Anghelache, Mihaela Turtoi, Anca Roxana Petrovici, Adrian Fifere, Mariana Pinteala, Manuela Calin
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Pharmaceutics
Subjects:
magnetic nanoparticles
dextran
protocatechuic acid
anti-inflammatory activity
endothelial cells
macrophages
Online Access:https://www.mdpi.com/1999-4923/13/9/1414

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