Efficacy of intravenous high-dose methotrexate in preventing relapse to the central nervous system in R-CHOP(-like)-treated, high-risk, diffuse large B-cell lymphoma patients and its effect on mortality: a systematic review and meta-analysis
CNS relapse in patients with diffuse large B-cell lymphoma (DLBCL) carries a dismal prognosis with most clinical guidelines recommending CNS prophylaxis to patients deemed at high risk for CNS relapse. However, results from observational studies investigating the effect of CNS prophylaxis have yiel...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Ferrata Storti Foundation
2024-03-01
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Series: | Haematologica |
Online Access: | https://haematologica.org/article/view/11506 |